PMID- 22628450 OWN - NLM STAT- MEDLINE DCOM- 20130530 LR - 20120726 IS - 1532-2092 (Electronic) IS - 1099-5129 (Linking) VI - 14 IP - 8 DP - 2012 Aug TI - ESC-EURObservational Research Programme: the Atrial Fibrillation Ablation Pilot Study, conducted by the European Heart Rhythm Association. PG - 1094-103 AB - AIMS: The Atrial Fibrillation Ablation Pilot Study is a prospective, multinational registry conducted by the European Heart Rhythm Association of the European Society of Cardiology that has been designed to describe the clinical epidemiology of patients undergoing an atrial fibrillation (AFib) ablation procedure, and the diagnostic/therapeutic processes applied in these patients across Europe. We present the results of the short-term (in-hospital) analysis. METHODS AND RESULTS: A total of 72 centres in 10 European countries were asked to enrol 20 consecutive patients scheduled for a first AFib ablation procedure. Between October 2010 and May 2011, 1410 patients were included, of which 1391 underwent an AFib ablation (98.7%). The median age was 60 years [inter-quartile range (IQR) 52-66], and 28% were females. Two-thirds presented paroxysmal AFib and 38% lone AFib. Symptoms were present in 86%. The indications for ablation were mostly symptomatic AFib, but in over a third of patients there was also a desire for a drug-free lifestyle and the maintenance of sinus rhythm. Pulmonary vein isolation was attempted in 98.4% of patients, the roof line in 21.3% and the mitral isthmus line in 12.8%. Complex-fractionated atrial electrograms were targeted in 17.9% and the ganglionated plexi in 3.3%. Complications occurred in 7.7%, of which 1.7% was major (i.e. cardiac perforation, myocardial infraction, endocarditis, cardiac arrest, stroke, hemothorax, pneumothorax, and sepsis). The median duration of hospitalization was 3 days (IQR 2-4). At discharge, 91.4% of patients were in sinus rhythm, 88.3% of patients were given vitamin K antagonists, and 67% antiarrhythmic medication. There was one death after the ablation procedure. CONCLUSION: The AFib Ablation Pilot Study provides crucial information on AF ablation in clinical practice across Europe. These data are relevant for further improvement of the management strategies of patients suffering from atrial fibrillation. FAU - Arbelo, Elena AU - Arbelo E AD - Department of Cardiology, Thorax Institute, Hospital Clinic de Barcelona, University of Barcelona, C/ Villarroel 170, 08036 Barcelona, Spain. FAU - Brugada, Josep AU - Brugada J FAU - Hindricks, Gerhard AU - Hindricks G FAU - Maggioni, Aldo AU - Maggioni A FAU - Tavazzi, Luigi AU - Tavazzi L FAU - Vardas, Panos AU - Vardas P FAU - Anselme, Frederic AU - Anselme F FAU - Inama, Giuseppe AU - Inama G FAU - Jais, Pierre AU - Jais P FAU - Kalarus, Zbigniew AU - Kalarus Z FAU - Kautzner, Josef AU - Kautzner J FAU - Lewalter, Thorsten AU - Lewalter T FAU - Mairesse, Georges AU - Mairesse G FAU - Perez-Villacastin, Julian AU - Perez-Villacastin J FAU - Riahi, Sam AU - Riahi S FAU - Taborsky, Milos AU - Taborsky M FAU - Theodorakis, George AU - Theodorakis G FAU - Trines, Serge AU - Trines S CN - Atrial Fibrillation Ablation Pilot Study Investigators LA - eng PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't DEP - 20120524 PL - England TA - Europace JT - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology JID - 100883649 RN - 0 (Anti-Arrhythmia Agents) SB - IM MH - Aged MH - Anti-Arrhythmia Agents/*therapeutic use MH - Atrial Fibrillation/drug therapy/physiopathology/*surgery MH - Catheter Ablation/*methods MH - Europe MH - Female MH - Heart Atria/physiopathology/*surgery MH - Humans MH - Male MH - Middle Aged MH - Observation MH - Pilot Projects MH - Prospective Studies MH - Treatment Outcome FIR - Brugada, Josep IR - Brugada J FIR - Arbelo, Elena IR - Arbelo E FIR - Hindriks, Gerhard IR - Hindriks G FIR - Maggioni, Aldo IR - Maggioni A FIR - Morgan, John IR - Morgan J FIR - Tavazzi, Luigi IR - Tavazzi L FIR - Vardas, Panos IR - Vardas P FIR - Alonso, Angeles IR - Alonso A FIR - Ferrari, Roberto IR - Ferrari R FIR - Komajda, Michel IR - Komajda M FIR - Tavazzi, Luigi IR - Tavazzi L FIR - Wood, David IR - Wood D FIR - Brugada, Josep IR - Brugada J FIR - Mairesse, Georges IR - Mairesse G FIR - Taborsky, Milos IR - Taborsky M FIR - Kautzner, Josef IR - Kautzner J FIR - Lewalter, Thorsten IR - Lewalter T FIR - Riahi, Sam IR - Riahi S FIR - Jais, Pierre IR - Jais P FIR - Anselme, Frederic IR - Anselme F FIR - Theodorakis, George IR - Theodorakis G FIR - Inama, Giuseppe IR - Inama G FIR - Trines, Serge IR - Trines S FIR - Kalarus, Zbigniew IR - Kalarus Z FIR - Perez Villacastin, Julian IR - Perez Villacastin J FIR - Maggioni, Aldo IR - Maggioni A FIR - Fiorucci, Emanuela IR - Fiorucci E FIR - Gracia, Gerard IR - Gracia G FIR - Laroche, Cecile IR - Laroche C FIR - Manini, Malika IR - Manini M FIR - Taylor, Charles IR - Taylor C FIR - Heidbuchel, H IR - Heidbuchel H FIR - Nuyens, D IR - Nuyens D FIR - Boland, J IR - Boland J FIR - Dinraths, V IR - Dinraths V FIR - Herzet, J-M IR - Herzet JM FIR - Hoffer, E IR - Hoffer E FIR - Malmendier, D IR - Malmendier D FIR - Massoz, M IR - Massoz M FIR - Pourbaix, S IR - Pourbaix S FIR - Ballant, E IR - Ballant E FIR - Blommaert, D IR - Blommaert D FIR - Deceuninck, O IR - Deceuninck O FIR - Dormal, F IR - Dormal F FIR - Xhaet, O IR - Xhaet O FIR - De Potter, T IR - 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Jensen HK FIR - Lukac, P IR - Lukac P FIR - Nielsen, J C IR - Nielsen JC FIR - Hansen, J IR - Hansen J FIR - Johannessen, A IR - Johannessen A FIR - Hansen, P S IR - Hansen PS FIR - Pedersen, A K IR - Pedersen AK FIR - Heath, F P IR - Heath FP FIR - Hjortshoj, S IR - Hjortshoj S FIR - Thogersen, A M IR - Thogersen AM FIR - Da Costa, A IR - Da Costa A FIR - Martel, I IR - Martel I FIR - Romeyer-Bouchard, C IR - Romeyer-Bouchard C FIR - Sadki, N IR - Sadki N FIR - Schmid, A IR - Schmid A FIR - Haissaguerre, M IR - Haissaguerre M FIR - Hocini, M IR - Hocini M FIR - Knecht, S IR - Knecht S FIR - Sacher, F IR - Sacher F FIR - Ait Said, M IR - Ait Said M FIR - Cauchemez, B IR - Cauchemez B FIR - Ledoux, F IR - Ledoux F FIR - Thomas, O IR - Thomas O FIR - Cebron, J-P IR - Cebron JP FIR - Decarsin, N IR - Decarsin N FIR - Gras, D IR - Gras D FIR - Hervouet, S IR - Hervouet S FIR - Durand, C IR - Durand C FIR - Durand-Dubief, A IR - Durand-Dubief A FIR - Poty, H IR - Poty H FIR - Babuty, D IR - Babuty D FIR - Pierre, B IR - Pierre B FIR - Albenque, J-P IR - Albenque JP FIR - Boveda, S IR - Boveda S FIR - Combes, N IR - Combes N FIR - Mas, R IR - Mas R FIR - Hermida, J-S IR - Hermida JS FIR - Kubala, M IR - Kubala M FIR - Godin, B IR - Godin B FIR - Savoure, A IR - Savoure A FIR - Soublin, Y IR - Soublin Y FIR - Defaye, P IR - Defaye P FIR - Jacon, P IR - Jacon P FIR - Brigadeau, F IR - Brigadeau F FIR - Corbut, S IR - Corbut S FIR - Flament-Balzola, F IR - Flament-Balzola F FIR - Kacet, S IR - Kacet S FIR - Klug, D IR - Klug D FIR - Lacroix, D IR - Lacroix D FIR - Copie, X IR - Copie X FIR - Gilles, L IR - Gilles L FIR - Hocine, Z IR - Hocine Z FIR - Paziaud, O IR - Paziaud O FIR - Piot, O IR - Piot O FIR - Crocq, C IR - Crocq C FIR - Kaballu, G IR - Kaballu G FIR - Le Moal, V IR - Le Moal V FIR - Lotton, P IR - Lotton P FIR - Mabo, P IR - Mabo P FIR - Pavin, D IR - Pavin D FIR - Andronache, M IR - Andronache M FIR - De Chillou, C IR - De Chillou C FIR - Magnin-Poull, I IR - Magnin-Poull I FIR - Deharo, J-C IR - Deharo JC FIR - Durand, C IR - Durand C FIR - Franceschi, F IR - Franceschi F FIR - Peyrouse, E IR - Peyrouse E FIR - Prevot, S IR - Prevot S FIR - Etchegoin, M IR - Etchegoin M FIR - Extramiana, F IR - Extramiana F FIR - Leenhardt, A IR - Leenhardt A FIR - Messali, A IR - Messali A FIR - Heine, T IR - Heine T FIR - Schneider, A IR - Schneider A FIR - Winter, N IR - Winter N FIR - Brachmann, J IR - Brachmann J FIR - Ritscher, G IR - Ritscher G FIR - Schertel-Gruenler, B IR - Schertel-Gruenler B FIR - Simon, H IR - Simon H FIR - Sinha, A-M IR - Sinha AM FIR - Turschner, O IR - Turschner O FIR - Wystrach, A IR - Wystrach A FIR - Stemberg, M IR - Stemberg M FIR - Kuck, K-H IR - Kuck KH FIR - Metzner, A IR - Metzner A FIR - Tilz, R IR - Tilz R FIR - Wissner, E IR - Wissner E FIR - Heitmann, K IR - Heitmann K FIR - Willems, S IR - Willems S FIR - Andresen, D IR - Andresen D FIR - Mueller, S IR - Mueller S FIR - Volkmer, M IR - Volkmer M FIR - Schmidt, B IR - Schmidt B FIR - Kostopoulou, A IR - Kostopoulou A FIR - Livanis, E IR - Livanis E FIR - Voudris, V IR - Voudris V FIR - Efremidis, M IR - Efremidis M FIR - Letsas, K IR - Letsas K FIR - Tsikrikas, S IR - Tsikrikas S FIR - Christoforatou, E IR - Christoforatou E FIR - Ioannidis, P IR - Ioannidis P FIR - Katsivas, A IR - Katsivas A FIR - Kourouklis, S IR - Kourouklis S FIR - Andrikopoulos, G IR - Andrikopoulos G FIR - Rassias, I IR - Rassias I FIR - Tzeis, S IR - Tzeis S FIR - Dakos, G IR - Dakos G FIR - Paraskevaidis, S IR - Paraskevaidis S FIR - Stavropoulos, G IR - Stavropoulos G FIR - Theofilogiannakos, E IR - Theofilogiannakos E FIR - Vassilikos, V P IR - Vassilikos VP FIR - Bongiorni, M G IR - Bongiorni MG FIR - Zucchelli, G IR - Zucchelli G FIR - Raviele, A IR - Raviele A FIR - Themistoclakis, S IR - Themistoclakis S FIR - Pratola, C IR - Pratola C FIR - Tritto, M IR - Tritto M FIR - Della Bella, P IR - Della Bella P FIR - Mazzone, P IR - Mazzone P FIR - Moltrasio, Moltrasio IR - Moltrasio M FIR - Tondo, C IR - Tondo C FIR - Calo, L IR - Calo L FIR - De Luca, L IR - De Luca L FIR - Guarracini, F IR - Guarracini F FIR - Lioy, E IR - Lioy E FIR - Dozza, L IR - Dozza L FIR - Frigoli, E IR - Frigoli E FIR - Giannelli, L IR - Giannelli L FIR - Pappone, C IR - Pappone C FIR - Saviano, M IR - Saviano M FIR - Schiavina, G IR - Schiavina G FIR - Vicedomini, G G IR - Vicedomini GG FIR - De Ponti, R IR - De Ponti R FIR - Doni, L A IR - Doni LA FIR - Marazzi, R IR - Marazzi R FIR - Salerno-Uriarte, J A IR - Salerno-Uriarte JA FIR - Tamborini, C IR - Tamborini C FIR - Anselmino, M IR - Anselmino M FIR - Ferraris, F IR - Ferraris F FIR - Gaita, F IR - Gaita F FIR - Bertaglia, E IR - Bertaglia E FIR - Brandolino, G IR - Brandolino G FIR - Zoppo, F IR - Zoppo F FIR - De Groot, N IR - De Groot N FIR - Janse, P IR - Janse P FIR - Jordaens, L IR - Jordaens L FIR - Pison, L IR - Pison L FIR - Roos, C IR - Roos C FIR - Van Gelder, I IR - Van Gelder I FIR - Manusama, R IR - Manusama R FIR - Meijer, A IR - Meijer A FIR - Van der Voort, P IR - Van der Voort P FIR - Trines, S IR - Trines S FIR - Kazmierczak, J IR - Kazmierczak J FIR - Kornacewicz-Jach, Z IR - Kornacewicz-Jach Z FIR - Wielusinski, M IR - Wielusinski M FIR - Baran, J IR - Baran J FIR - Kulakowski, P IR - Kulakowski P FIR - Dzidowski, M IR - Dzidowski M FIR - Fuglewicz, A IR - Fuglewicz A FIR - Nowak, K IR - Nowak K FIR - Pruszkowska-Skrzep, P IR - Pruszkowska-Skrzep P FIR - Wozniak, A IR - Wozniak A FIR - Nowak, S IR - Nowak S FIR - Trusz-Gluza, M IR - Trusz-Gluza M FIR - Almendral, J IR - Almendral J FIR - Atienza, F IR - Atienza F FIR - Castellanos, E IR - Castellanos E FIR - De Diego, C IR - De Diego C FIR - Ortiz, M IR - Ortiz M FIR - Moreno Planas, J IR - Moreno Planas J FIR - Perez Castellano, N IR - Perez Castellano N FIR - Benezet, J IR - Benezet J FIR - Farre Muncharaz, J IR - Farre Muncharaz J FIR - Rubio Campal, J M IR - Rubio Campal JM FIR - Hernandez Madrid, A IR - Hernandez Madrid A FIR - Matia, R IR - Matia R FIR - Arana, E IR - Arana E FIR - Pedrote, A IR - Pedrote A FIR - Cozar, A IR - Cozar A FIR - Peinado, R IR - Peinado R FIR - Valverde, I IR - Valverde I FIR - Arbelo, E IR - Arbelo E FIR - Berruezo, A IR - Berruezo A FIR - Calvo, N IR - Calvo N FIR - Guiu, E IR - Guiu E FIR - Husseini, S IR - Husseini S FIR - Mont Girbau, L IR - Mont Girbau L EDAT- 2012/05/26 06:00 MHDA- 2013/06/01 06:00 CRDT- 2012/05/26 06:00 PHST- 2012/05/26 06:00 [entrez] PHST- 2012/05/26 06:00 [pubmed] PHST- 2013/06/01 06:00 [medline] AID - eus153 [pii] AID - 10.1093/europace/eus153 [doi] PST - ppublish SO - Europace. 2012 Aug;14(8):1094-103. doi: 10.1093/europace/eus153. Epub 2012 May 24.