PMID- 22642432
OWN - NLM
STAT- MEDLINE
DCOM- 20120815
LR  - 20120530
IS  - 1943-281X (Electronic)
IS  - 0033-2747 (Linking)
VI  - 75
IP  - 2
DP  - 2012 Summer
TI  - Considering DSM-5: personality diagnostics in patients with schizophrenia 
      spectrum disorders.
PG  - 120-34
LID - 10.1521/psyc.2012.75.2.120 [doi]
AB  - The aims of this study were to examine the prevalence of personality disorders 
      (PD) in patients with schizophrenia spectrum disorders (SSD), to examine the 
      interaction of axis-I and axis-II symptoms to provide an estimate on the 
      confounding potential of SSD psychopathology in the establishment of DSM-IV PD 
      diagnoses, and to discuss implications concerning the proposed changes in DSM-5. 
      Patients with SSD, aged 18 to 65 years, and being at least partially remitted 
      (PANSS total score < 75) were included. PD was examined categorically and 
      dimensionally using the SCID-II screening questionnaire and interview, and SSD 
      psychopathology was rated using the Positive and Negative Syndrome Scale for 
      Schizophrenia (PANSS). Forty-five patients (31 with schizophrenia) were included 
      in the current study. Mean age was 37.2 years, and the median duration of illness 
      was 9.5 years. Mean PANSS total score was 42.5. The cumulative prevalence of PD 
      in our collective was 20%, with obsessive-compulsive, antisocial, and borderline 
      PD being the most frequent. There were no cases of cluster A PD diagnoses. In the 
      dimensional analysis, numerous correlations of small to medium effect size 
      emerged between maladaptive personality traits and SSD psychopathology. PD is 
      present in a clinically relevant subgroup of SSD patients and has to be 
      recognized in SSD treatment. Currently, it remains unclear to what extent 
      correlations between personality traits and SSD symptoms can be explained by 
      content overlap or co-variation of SSD psychopathology and PD traits. SSD 
      psychopathology may bias PD diagnostics and lead to a higher percentage of 
      categorical PD diagnoses, especially considering the proposed changes in DSM-5.
FAU - Schroeder, Katrin
AU  - Schroeder K
AD  - Department of Psychiatry and Psychotherapy, University Medical Centre 
      Hamburg-Eppendorf, Hamburg, Germany. katrin.schroeder@uke-hh.de
FAU - Hoppe, Annelene
AU  - Hoppe A
FAU - Andresen, Burghard
AU  - Andresen B
FAU - Naber, Dieter
AU  - Naber D
FAU - Lammers, Claas-Hinrich
AU  - Lammers CH
FAU - Huber, Christian G
AU  - Huber CG
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Psychiatry
JT  - Psychiatry
JID - 0376470
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - *Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Humans
MH  - Interview, Psychological
MH  - Male
MH  - Middle Aged
MH  - Personality Disorders/classification/diagnosis/*epidemiology
MH  - Prevalence
MH  - Psychiatric Status Rating Scales
MH  - Schizophrenia/diagnosis/*epidemiology
MH  - *Schizophrenic Psychology
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2012/05/31 06:00
MHDA- 2012/08/16 06:00
CRDT- 2012/05/31 06:00
PHST- 2012/05/31 06:00 [entrez]
PHST- 2012/05/31 06:00 [pubmed]
PHST- 2012/08/16 06:00 [medline]
AID - 10.1521/psyc.2012.75.2.120 [doi]
PST - ppublish
SO  - Psychiatry. 2012 Summer;75(2):120-34. doi: 10.1521/psyc.2012.75.2.120.