PMID- 22643289
OWN - NLM
STAT- MEDLINE
DCOM- 20121126
LR  - 20120807
IS  - 1095-9513 (Electronic)
IS  - 1055-7903 (Linking)
VI  - 65
IP  - 1
DP  - 2012 Oct
TI  - Phylogenetic analysis of Primula section Primula reveals rampant non-monophyly 
      among morphologically distinct species.
PG  - 23-34
LID - 10.1016/j.ympev.2012.05.015 [doi]
AB  - The type section of Primula (Primulaceae), here considered to include seven 
      species, is phylogenetically quite isolated in its genus. Although its species 
      are popular ornamentals, traditional medicinal plants and model organisms for the 
      study of heterostyly, the section has not yet been studied from a phylogenetic or 
      evolutionary perspective. Using phylogenetic analysis of nuclear ITS and plastid 
      data from all species and subspecies, we find that widespread Primula elatior is 
      genetically heterogeneous and non-monophyletic to most if not all of the other 
      ingroup taxa. The Genealogical Sorting Index (GSI) indicates that the assumption 
      of all currently accepted species being independent lineages is consistent with 
      the data. It is possible that P. elatior in its current circumscription may 
      represents the disjointed remnant of an ancestral species from which the other 
      recognized species diverged. However, based on available data, the alternative 
      possibility of introgression explaining the non-monophyly of this species cannot 
      be excluded. Species trees show P. elatior and P. veris as sister species. 
      Primula vulgaris and P. juliae are closely related, while, in contrast to 
      previous assumptions, P. renifolia does not appear to be a close relative of P. 
      megaseifolia. With the section's isolation from the rest of the genus and very 
      short internal branches, our dataset also presents a case study of the 
      confounding effects of different branch length priors on the Bayesian estimation 
      of resulting branch length estimates. Experimental runs using different priors 
      confirm the problem of resulting estimates varying by orders of magnitude, while 
      topology and relative branch lengths seem unaffected.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Schmidt-Lebuhn, Alexander N
AU  - Schmidt-Lebuhn AN
AD  - Institute of Systematic Botany, University of Zurich, Zurich, Switzerland. 
      alexander.schmidt-lebuhn@csiro.au
FAU - de Vos, Jurriaan M
AU  - de Vos JM
FAU - Keller, Barbara
AU  - Keller B
FAU - Conti, Elena
AU  - Conti E
LA  - eng
PT  - Journal Article
DEP - 20120527
PL  - United States
TA  - Mol Phylogenet Evol
JT  - Molecular phylogenetics and evolution
JID - 9304400
RN  - 0 (DNA, Chloroplast)
RN  - 0 (DNA, Plant)
RN  - 0 (DNA, Ribosomal Spacer)
SB  - IM
MH  - Bayes Theorem
MH  - Cell Nucleus/genetics
MH  - DNA, Chloroplast/genetics
MH  - DNA, Plant/genetics
MH  - DNA, Ribosomal Spacer/genetics
MH  - Likelihood Functions
MH  - Models, Genetic
MH  - *Phylogeny
MH  - Primula/*classification/genetics
MH  - Sequence Analysis, DNA
EDAT- 2012/05/31 06:00
MHDA- 2012/12/10 06:00
CRDT- 2012/05/31 06:00
PHST- 2012/02/24 00:00 [received]
PHST- 2012/05/11 00:00 [revised]
PHST- 2012/05/16 00:00 [accepted]
PHST- 2012/05/31 06:00 [entrez]
PHST- 2012/05/31 06:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
AID - S1055-7903(12)00193-5 [pii]
AID - 10.1016/j.ympev.2012.05.015 [doi]
PST - ppublish
SO  - Mol Phylogenet Evol. 2012 Oct;65(1):23-34. doi: 10.1016/j.ympev.2012.05.015. Epub 
      2012 May 27.