PMID- 22647328
OWN - NLM
STAT- MEDLINE
DCOM- 20120809
LR  - 20120531
IS  - 0021-5252 (Print)
IS  - 0021-5252 (Linking)
VI  - 65
IP  - 6
DP  - 2012 Jun
TI  - [Thymic carcinoid associated with multiple endocrine neoplasia type 1].
PG  - 466-9
AB  - We report a case of a thymic carcinoid associated with multiple endocrine 
      neoplasia type 1( MEN-1). A 37-year-old man was referred to our hospital for 
      further examination of an abnormal chest shadow. A chest computed tomography (CT) 
      showed an anterior mediastinal mass measuring 6.5 cm in diameter. A pathological 
      diagnosis of thymic carcinoid was made from a CT-guided needle biopsy specimen. 
      Preoperative workup including endocrinological examination revealed a pituitary 
      adenoma and hyperparathyroidism, and MEN-1 was clinically diagnosed. We performed 
      total parathyroidectomy with autotransplantation and thymectomy with lymph node 
      dissection through cervical collar incision and median sternotomy. The diagnosis 
      of MEN-1 was confirmed by the genomic analysis postoperatively. Since 25% of 
      thymic carcinoids are MEN-1 related and 95% of MEN-1 patients develop 
      hyperparathyroidism, it should be kept in mind that this condition can be treated 
      by thymectomy and concurrent parathyroidectomy.
FAU - Ishida, Itaru
AU  - Ishida I
AD  - Department of Thoracic Surgery, Iwate Prefectural Central Hospital, Morioka, 
      Japan.
FAU - Oura, Hiroyuki
AU  - Oura H
FAU - Niikawa, Hiromichi
AU  - Niikawa H
FAU - Onodera, Ken
AU  - Onodera K
FAU - Handa, Masashi
AU  - Handa M
FAU - Onuki, Koji
AU  - Onuki K
FAU - Kawamura, Minoru
AU  - Kawamura M
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Kyobu Geka
JT  - Kyobu geka. The Japanese journal of thoracic surgery
JID - 0413533
SB  - IM
MH  - Adult
MH  - Carcinoid Tumor/*complications/surgery
MH  - Humans
MH  - Hyperparathyroidism/complications
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/*complications/*surgery
MH  - Parathyroid Neoplasms/*complications/surgery
MH  - Parathyroidectomy
MH  - Thymectomy
MH  - Thymus Neoplasms/*complications/surgery
EDAT- 2012/06/01 06:00
MHDA- 2012/08/10 06:00
CRDT- 2012/06/01 06:00
PHST- 2012/06/01 06:00 [entrez]
PHST- 2012/06/01 06:00 [pubmed]
PHST- 2012/08/10 06:00 [medline]
PST - ppublish
SO  - Kyobu Geka. 2012 Jun;65(6):466-9.