PMID- 22648250
OWN - NLM
STAT- MEDLINE
DCOM- 20120926
LR  - 20211021
IS  - 1643-3750 (Electronic)
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 18
IP  - 6
DP  - 2012 Jun
TI  - Hemorheological responses to progressive resistance exercise training in healthy 
      young males.
PG  - CR351-60
AB  - BACKGROUND: This study aimed to explore the effects of progressive resistance 
      exercise training (PRET) on hemorheology. MATERIAL/METHODS: Exercise sessions 
      included 1-3 sets of 8-12 repetitions at 40-60% of 1-repetition maximum (1-RM) 
      for 3 weeks and at 75-80% of 1-RM during weeks 4-12. Red blood cell (RBC) 
      deformability and aggregation were determined by ektacytometry, plasma and whole 
      blood viscosities (WBV) by rotational viscometry. Lactate concentration was 
      evaluated by an analyzer and fibrinogen was evaluated by coagulometry. Plasma 
      total oxidant/antioxidant status was measured by colorimetry. RESULTS: Following 
      an acute increase after exercise on the first day, RBC deformability was elevated 
      during weeks 3 and 4 (p=0.028; p=0.034, respectively). The last exercise protocol 
      applied in week 12 again caused an acute increase in this parameter (p=0.034). 
      RBC aggregation was increased acutely on the first day, but decreased after that 
      throughout the protocol (p<0.05). At weeks 4 and 12 pre-exercise measurements of 
      WBV at standard hematocrit and plasma viscosity were decreased (p=0.05; p=0.041, 
      respectively), while post-exercise values were increased (p=0.005; p=0.04, 
      respectively). Post-exercise WBV at autologous hematocrit measured at week 12 was 
      increased (p=0.01). Lactate was elevated after each exercise session (p<0.05). 
      Fibrinogen was decreased on the third week (p<0.01), while it was increased on 
      the 4th week (p=0.005). Plasma antioxidant status was increased at week 3 
      (p=0.034) and oxidative stress index was decreased at week 4 (p=0.013) after 
      exercise. CONCLUSIONS: The results of this study indicate that PRET may have 
      positive effects on hemorheological parameters.
FAU - Kilic-Toprak, Emine
AU  - Kilic-Toprak E
AD  - Pamukkale University, Faculty of Medicine, Department of Physiology, Kinikli, 
      Denizli, Turkey.
FAU - Ardic, Fusun
AU  - Ardic F
FAU - Erken, Gulten
AU  - Erken G
FAU - Unver-Kocak, Fatma
AU  - Unver-Kocak F
FAU - Kucukatay, Vural
AU  - Kucukatay V
FAU - Bor-Kucukatay, Melek
AU  - Bor-Kucukatay M
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
RN  - 0 (Antioxidants)
RN  - 0 (Oxidants)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 9001-32-5 (Fibrinogen)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Antioxidants/metabolism
MH  - Blood Viscosity/physiology
MH  - Erythrocyte Aggregation/physiology
MH  - Erythrocyte Deformability/physiology
MH  - Erythrocytes/physiology
MH  - Exercise/*physiology
MH  - Fibrinogen/metabolism
MH  - *Health
MH  - Hemorheology/*physiology
MH  - Humans
MH  - Lactic Acid/blood
MH  - Male
MH  - Oxidants/blood
MH  - Oxidative Stress
MH  - Oxygen/metabolism
MH  - *Resistance Training
MH  - Time Factors
MH  - Young Adult
PMC - PMC3560717
EDAT- 2012/06/01 06:00
MHDA- 2012/09/27 06:00
PMCR- 2012/06/01
CRDT- 2012/06/01 06:00
PHST- 2012/06/01 06:00 [entrez]
PHST- 2012/06/01 06:00 [pubmed]
PHST- 2012/09/27 06:00 [medline]
PHST- 2012/06/01 00:00 [pmc-release]
AID - 882878 [pii]
AID - 10.12659/msm.882878 [doi]
PST - ppublish
SO  - Med Sci Monit. 2012 Jun;18(6):CR351-60. doi: 10.12659/msm.882878.