PMID- 22660522
OWN - NLM
STAT- MEDLINE
DCOM- 20130703
LR  - 20211021
IS  - 1432-1971 (Electronic)
IS  - 0172-0643 (Linking)
VI  - 34
IP  - 1
DP  - 2013 Jan
TI  - Left atrial volume change throughout the cardiac cycle in children with 
      congenital heart disease associated with increased pulmonary blood flow: 
      evaluation using a novel left atrium-tracking method.
PG  - 105-11
LID - 10.1007/s00246-012-0395-4 [doi]
AB  - There is a paucity of data regarding the significance of left atrial (LA) volume 
      and its changes throughout the cardiac cycle in pediatric patients with heart 
      disease. The recently developed LA volume-tracking (LAVT) method can 
      automatically construct the LA volume curve. The study group consisted of 48 
      pediatric patients with ventricular septal defect (n = 34) or patent ductus 
      arteriosus (n = 14) and age-matched healthy controls. Maximum and minimum LA 
      volumes (LAVmax and LAVmin, respectively) were measured. The total LA emptying 
      volume (LAVtotal) was defined as LAVmax--LAVmin. Volume parameters were 
      standardized by dividing by body surface area (BSA). The total LA emptying 
      fraction (%LAVtotal) was defined as the ratio of LAVtotal to LAVmax. In the 
      patient group, there was a positive correlation between the ratio of pulmonary to 
      systemic blood flow (Qp/Qs) and LAVmax/BSA, LAVmin/BSA, and LAVtotal/BSA (r = 
      0.42, 0.44, and 0.34, respectively). LAVmin/BSA was positively correlated with 
      the ratio of early mitral inflow velocity to early mitral annular diastolic 
      tissue Doppler velocity (E/E') (r = 0.32). The %LAVtotal had a negative 
      correlation with left-ventricular (LV) end-diastolic pressure (r = -0.32). There 
      were significant correlations between serum B-type natriuretic peptide level and 
      LAVmax/BSA, LAVmin/BSA, and %LAVtotal (r = 0.38, 0.49, and -0.35, respectively). 
      The LAVT method is useful in the evaluation of LV diastolic function in pediatric 
      patients with chronic LV volume overload.
FAU - Sakata, Miho
AU  - Sakata M
AD  - Department of Pediatrics, School of Medicine, University of Tokushima, Tokushima 
      770-8503, Japan. mhsakata@clin.med.tokushima-u.ac.jp
FAU - Hayabuchi, Yasunobu
AU  - Hayabuchi Y
FAU - Inoue, Miki
AU  - Inoue M
FAU - Onishi, Tatsuya
AU  - Onishi T
FAU - Kagami, Shoji
AU  - Kagami S
LA  - eng
PT  - Journal Article
DEP - 20120604
PL  - United States
TA  - Pediatr Cardiol
JT  - Pediatric cardiology
JID - 8003849
SB  - IM
MH  - Atrial Function, Left/*physiology
MH  - Cardiac Catheterization
MH  - Child
MH  - Child, Preschool
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Atria/diagnostic imaging/*physiopathology
MH  - Heart Defects, Congenital/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Male
MH  - Observer Variation
MH  - Pulmonary Circulation/*physiology
EDAT- 2012/06/05 06:00
MHDA- 2013/07/05 06:00
CRDT- 2012/06/05 06:00
PHST- 2011/12/28 00:00 [received]
PHST- 2012/05/11 00:00 [accepted]
PHST- 2012/06/05 06:00 [entrez]
PHST- 2012/06/05 06:00 [pubmed]
PHST- 2013/07/05 06:00 [medline]
AID - 10.1007/s00246-012-0395-4 [doi]
PST - ppublish
SO  - Pediatr Cardiol. 2013 Jan;34(1):105-11. doi: 10.1007/s00246-012-0395-4. Epub 2012 
      Jun 4.