PMID- 22661666
OWN - NLM
STAT- MEDLINE
DCOM- 20120816
LR  - 20120604
IS  - 1471-8405 (Electronic)
IS  - 0962-7480 (Linking)
VI  - 62
IP  - 4
DP  - 2012 Jun
TI  - Occupational asthma due to spruce wood.
PG  - 301-4
LID - 10.1093/occmed/kqs023 [doi]
AB  - Workers exposed to a variety of wood dusts are known to experience work-related 
      respiratory symptoms, including occupational asthma. There are, however, few 
      reports of occupational asthma due to spruce wood. We present the case of a 
      31-year-old sawmill owner with severe asthma caused by exposure to spruce wood 
      dust, who developed asthmatic symptoms after 2 years of working. Investigations 
      included clinical examination, routine laboratory tests, spirometry, chest X-ray, 
      total serum immunoglobulin E (IgE) and specific serum IgEs against various woods 
      and other occupational allergens. Additionally, we monitored the peak expiratory 
      flow rate (PEFR) and symptom score both at work and when off work. Specific serum 
      IgE for spruce wood was detected (7.8 IU/ml). The results of PEFR and workplace 
      symptom-score monitoring, coupled with an elevated eosinophil count in induced 
      sputum, supported the diagnosis of occupational asthma. To our knowledge, this is 
      the first well-documented case of occupational asthma induced by spruce wood 
      dust. A type I immunological mechanism seems to be responsible.
FAU - Wittczak, T
AU  - Wittczak T
AD  - Department of Occupational Diseases and Toxicology, Nofer Institute of 
      Occupational Medicine, Lodz, Poland. tomekwit@imp.lodz.pl
FAU - Dudek, W
AU  - Dudek W
FAU - Walusiak-Skorupa, J
AU  - Walusiak-Skorupa J
FAU - Bochenska-Marciniak, M
AU  - Bochenska-Marciniak M
FAU - Nowakowska-Swirta, E
AU  - Nowakowska-Swirta E
FAU - Kuna, P
AU  - Kuna P
FAU - Palczynski, C
AU  - Palczynski C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Occup Med (Lond)
JT  - Occupational medicine (Oxford, England)
JID - 9205857
RN  - 0 (Dust)
SB  - IM
MH  - Adult
MH  - Asthma, Occupational/*etiology
MH  - *Dust
MH  - Humans
MH  - Male
MH  - Occupational Exposure/*adverse effects
MH  - Picea/*toxicity
MH  - Wood/*toxicity
EDAT- 2012/06/05 06:00
MHDA- 2012/08/17 06:00
CRDT- 2012/06/05 06:00
PHST- 2012/06/05 06:00 [entrez]
PHST- 2012/06/05 06:00 [pubmed]
PHST- 2012/08/17 06:00 [medline]
AID - kqs023 [pii]
AID - 10.1093/occmed/kqs023 [doi]
PST - ppublish
SO  - Occup Med (Lond). 2012 Jun;62(4):301-4. doi: 10.1093/occmed/kqs023.