PMID- 22665572
OWN - NLM
STAT- MEDLINE
DCOM- 20130201
LR  - 20211021
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2012
DP  - 2012 Feb 25
TI  - Management of a large retroperitoneal primitive neuroectodermal tumour: 'a 
      multimodal approach'.
LID - 10.1136/bcr.12.2011.5459 [doi]
LID - bcr1220115459
AB  - Retroperitoneal primitive neuroectodermal tumour (PNET) is a rare disease having 
      poor prognosis. Treatment mainly consists of en block resection of the tumour to 
      achieve RO resection, however multimodal approach has also been used with 
      improved survival. The authors report a 40-year-old male with large 
      retroperitoneal PNET adherent to aorta and compressing the inferior vena cava. He 
      was subjected to P6 protocol chemotherapy (cyclophosphamide, adriamycin, 
      vincristine, ifosfamide and etoposide) in view of borderline operability. 
      Postchemotherapy contrast enhanced CT revealed significant reduction in size of 
      the lesion. He underwent complete resection of the tumour followed by concurrent 
      chemoradiation. He remains asymptomatic on follow-up over a period of 2 years.
FAU - Sable, Shailesh
AU  - Sable S
AD  - Gastrointestinal Surgery Department, Jaslok Hospital, Mumbai, India.
FAU - Gandhi, Vidhyachandra
AU  - Gandhi V
FAU - Nagral, Aabha
AU  - Nagral A
FAU - Nagral, Sanjay
AU  - Nagral S
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120225
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 5J49Q6B70F (Vincristine)
RN  - 6PLQ3CP4P3 (Etoposide)
RN  - 80168379AG (Doxorubicin)
RN  - 8N3DW7272P (Cyclophosphamide)
RN  - UM20QQM95Y (Ifosfamide)
RN  - IVAD protocol
SB  - IM
MH  - Adult
MH  - Antineoplastic Combined Chemotherapy Protocols/administration & 
      dosage/therapeutic use
MH  - Combined Modality Therapy
MH  - Cyclophosphamide/administration & dosage/therapeutic use
MH  - Doxorubicin/administration & dosage/therapeutic use
MH  - Etoposide/administration & dosage/therapeutic use
MH  - Humans
MH  - Ifosfamide/administration & dosage/therapeutic use
MH  - Male
MH  - Neuroectodermal Tumors, Primitive/diagnostic imaging/drug 
      therapy/pathology/surgery/*therapy
MH  - Retroperitoneal Neoplasms/diagnostic imaging/drug 
      therapy/pathology/surgery/*therapy
MH  - Tomography, X-Ray Computed
MH  - Vincristine/administration & dosage/therapeutic use
PMC - PMC3291040
COIS- Competing interests None.
EDAT- 2012/06/06 06:00
MHDA- 2013/02/05 06:00
PMCR- 2014/02/28
CRDT- 2012/06/06 06:00
PHST- 2012/06/06 06:00 [entrez]
PHST- 2012/06/06 06:00 [pubmed]
PHST- 2013/02/05 06:00 [medline]
PHST- 2014/02/28 00:00 [pmc-release]
AID - bcr.12.2011.5459 [pii]
AID - 10.1136/bcr.12.2011.5459 [doi]
PST - epublish
SO  - BMJ Case Rep. 2012 Feb 25;2012:bcr1220115459. doi: 10.1136/bcr.12.2011.5459.