PMID- 22667085
OWN - NLM
STAT- MEDLINE
DCOM- 20130712
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 1
DP  - 2012 Jan
TI  - [Determination of seven toxaphene congeners in ginseng and milkvetch root by gas 
      chromatography tandem mass spectrometry].
PG  - 14-20
AB  - A novel method for the determination of representative toxaphene congeners in 
      traditional Chinese herbal medicines was developed. Ginseng and Milkvetch Root 
      were selected as the samples and seven toxaphene congeners were selected as the 
      monitoring objects. The samples were extracted by accelerated solvent extraction 
      with cyclohexane-acetone (9:1, v/v), then cleaned-up by Florisil solid phase 
      extraction with hexane as the eluent and the residues were detected by gas 
      chromatography-electron ionization tandem mass spectrometry (GC-EI-MS/MS) in 
      multiple reaction monitoring (MRM) mode. The performance was demonstrated by the 
      analysis of Ginseng and Milkvetch Root samples spiked with toxaphene congeners at 
      three concentration levels of 0.005, 0.01 and 0.1 mg/kg. The recoveries ranged 
      from 72.4% to 105% with the relative standard deviations (RSDs) of 0.96%-10.4%. 
      The limits of detection (LODs) were 0.2-1.7 microg/kg. This method is sensitive 
      and efficient in the aspect of extraction, and can be applied to monitor the 
      residue of toxaphene congeners in Ginseng and Milkvetch Root.
FAU - Tian, Shaoqiong
AU  - Tian S
AD  - Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China.
FAU - Mao, Xiuhong
AU  - Mao X
FAU - Miao, Shui
AU  - Miao S
FAU - Jia, Zhengwei
AU  - Jia Z
FAU - Wang, Ke
AU  - Wang K
FAU - Ji, Shen
AU  - Ji S
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Insecticides)
RN  - 0 (Pesticide Residues)
RN  - 8001-35-2 (Toxaphene)
SB  - IM
MH  - Astragalus Plant/*chemistry
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Insecticides/analysis
MH  - Panax/*chemistry
MH  - Pesticide Residues/analysis
MH  - Plant Roots/chemistry
MH  - Tandem Mass Spectrometry/*methods
MH  - Toxaphene/analogs & derivatives/*analysis
EDAT- 2012/06/07 06:00
MHDA- 2013/07/16 06:00
CRDT- 2012/06/07 06:00
PHST- 2012/06/07 06:00 [entrez]
PHST- 2012/06/07 06:00 [pubmed]
PHST- 2013/07/16 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.09019 [doi]
PST - ppublish
SO  - Se Pu. 2012 Jan;30(1):14-20. doi: 10.3724/sp.j.1123.2011.09019.