PMID- 22672914
OWN - NLM
STAT- MEDLINE
DCOM- 20121011
LR  - 20230620
IS  - 1349-9092 (Electronic)
IS  - 0917-5040 (Print)
IS  - 0917-5040 (Linking)
VI  - 22
IP  - 4
DP  - 2012
TI  - BMI is strongly associated with hypertension, and waist circumference is strongly 
      associated with type 2 diabetes and dyslipidemia, in northern Chinese adults.
PG  - 317-23
AB  - BACKGROUND: Obesity is closely associated with chronic diseases such as 
      hypertension, type 2 diabetes mellitus (T2DM), and dyslipidemia. We analyzed the 
      optimal obesity index cut-off values for metabolic syndrome (MetS), and 
      identified the obesity index that is more closely associated with these chronic 
      diseases, in a population of northern Chinese. METHODS: We surveyed 8940 adults 
      (age, 20-74 years) living in northern China for chronic diseases. Receiver 
      operating characteristics (ROC) analysis, relative risk, and multivariate 
      regression were used to develop an appropriate index and optimal cut-off values 
      for MetS and obesity-related chronic diseases. RESULTS: Waist circumference (WC) 
      and body mass index (BMI) were good markers for MetS, WC was a good marker for 
      T2DM and dyslipidemia, and BMI was a good marker for hypertension. The optimal 
      BMI cut-off value of MetS was 24 kg/m(2), and the optimal WC cut-offs were 86 cm 
      and 78 cm in men and women, respectively. Relative risk regression models showed 
      that BMI was associated with hypertension, T2DM, and hypertriglyceridemia and a 
      higher prevalence ratio (PR) for hypertension: 2.35 (95% CI, 2.18-2.50). WC was 
      associated with T2DM, hypertension, and hypertriglyceridemia, with PRs of 2.05 
      (1.63-2.55) for T2DM and 2.47 (2.04-2.85) for hypertriglyceridemia. In 
      multivariate regression models, the standardized regression coefficients (SRCs) 
      of BMI were greater for SBP and DBP, and the SRC of WC was greater for fasting 
      blood glucose, 2-hour postload blood glucose, triglyceride, and total 
      cholesterol. CONCLUSIONS: Our analysis of a population of northern Chinese 
      indicates that the optimal cut-off values for MetS are WCs of 86 cm in men and 78 
      cm in women and a BMI of 24 kg/m(2) in both sexes. BMI was strongly associated with 
      hypertension, while WC was strongly associated with T2DM and dyslipidemia.
FAU - Feng, Ren-Nan
AU  - Feng RN
AD  - Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical 
      University, P R China.
FAU - Zhao, Chen
AU  - Zhao C
FAU - Wang, Cheng
AU  - Wang C
FAU - Niu, Yu-Cun
AU  - Niu YC
FAU - Li, Kang
AU  - Li K
FAU - Guo, Fu-Chuan
AU  - Guo FC
FAU - Li, Song-Tao
AU  - Li ST
FAU - Sun, Chang-Hao
AU  - Sun CH
FAU - Li, Ying
AU  - Li Y
LA  - eng
GR  - K99 AA023002/AA/NIAAA NIH HHS/United States
GR  - R00 AA023002/AA/NIAAA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120510
PL  - Japan
TA  - J Epidemiol
JT  - Journal of epidemiology
JID - 9607688
SB  - IM
MH  - Adult
MH  - Aged
MH  - Anthropometry/methods
MH  - *Body Mass Index
MH  - China/epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Dyslipidemias/*epidemiology
MH  - Female
MH  - Humans
MH  - Hypertension/*epidemiology
MH  - Male
MH  - Metabolic Syndrome/epidemiology
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Obesity/complications
MH  - ROC Curve
MH  - Risk Factors
MH  - *Waist Circumference
MH  - Young Adult
PMC - PMC3798650
EDAT- 2012/06/08 06:00
MHDA- 2012/10/12 06:00
PMCR- 2012/07/05
CRDT- 2012/06/08 06:00
PHST- 2012/06/08 06:00 [entrez]
PHST- 2012/06/08 06:00 [pubmed]
PHST- 2012/10/12 06:00 [medline]
PHST- 2012/07/05 00:00 [pmc-release]
AID - DN/JST.JSTAGE/jea/JE20110120 [pii]
AID - JE20110120 [pii]
AID - 10.2188/jea.je20110120 [doi]
PST - ppublish
SO  - J Epidemiol. 2012;22(4):317-23. doi: 10.2188/jea.je20110120. Epub 2012 May 10.