PMID- 22673720 OWN - NLM STAT- MEDLINE DCOM- 20130306 LR - 20190606 IS - 1347-7439 (Electronic) IS - 0916-7250 (Linking) VI - 74 IP - 9 DP - 2012 Sep TI - Studies on hantavirus infection in small mammals captured in southern and central highland area of Vietnam. PG - 1155-62 AB - To investigate the distribution of hantaviruses among animals in Southern and Central Highland area of Vietnam, a total of 1311 serum samples were obtained from rats and Asian house shrews (Suncus murinus) captured at 11 locations between 2006 and 2009. A total of 1066 serum samples from rats were examined for IgG antibodies against Hantaan virus, and there were 30 antibody-positive serum samples from rats that had been captured mainly in a port area and urban area in Ho Chi Minh City (HCMC) (2.8%). All of the antibody-positive rats were Rattus norvegicus, and they had Seoul virus (SEOV) genome in their lungs. SEOV sequences detected from rats captured in Southern Vietnam belonged to the same lineage as those from rats captured at Haiphong Port and a market area in Hanoi City. SEOV strain CSG5 was isolated from a rat captured at Saigon Harbor. Strain CSG5 showed a cross-neutralization pattern almost the same as that of a representative strain of SEOV. A total of 245 Asian house shrews were captured in the Central Highland area and near HCMC. Sera were examined for IgG antibodies against Thottapalayam virus (TPMV), and 32 (13.1%) of the antibody-positive shrews were mainly from the Central Highland area and showed a neutralizing antibody against TPMV. These results indicated that SEOV is distributed among R. norvegicus inhabiting harbor and urban areas of Southern Vietnam and that TPMV or an antigenically related virus is distributed among Asian house shrews in Central Highland area. FAU - Luan, Vu Dinh AU - Luan VD AD - Pasteur Institute, 8 Ward, 3 District, Ho Chi Minh City, Vietnam. FAU - Yoshimatsu, Kumiko AU - Yoshimatsu K FAU - Endo, Rika AU - Endo R FAU - Taruishi, Midori AU - Taruishi M FAU - Huong, Vo Thi AU - Huong VT FAU - Dat, Dang Tuan AU - Dat DT FAU - Tien, Pham Cong AU - Tien PC FAU - Shimizu, Kenta AU - Shimizu K FAU - Koma, Takaaki AU - Koma T FAU - Yasuda, Shumpei P AU - Yasuda SP FAU - Nhi, Le AU - Nhi L FAU - Huong, Vu Thi Que AU - Huong VT FAU - Arikawa, Jiro AU - Arikawa J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20120522 PL - Japan TA - J Vet Med Sci JT - The Journal of veterinary medical science JID - 9105360 RN - 0 (Antibodies, Viral) RN - 0 (DNA Primers) RN - 0 (Immunoglobulin G) SB - IM MH - Animals MH - Antibodies, Viral/blood MH - Base Sequence MH - Blotting, Western/veterinary MH - Cluster Analysis MH - DNA Primers/genetics MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Fluorescent Antibody Technique, Indirect/veterinary MH - Hantavirus Infections/*epidemiology/*veterinary MH - Immunoglobulin G/blood MH - Lung/virology MH - Molecular Sequence Data MH - Neutralization Tests/veterinary MH - Phylogeny MH - Prevalence MH - Rats/*virology MH - Seoul virus/genetics/*isolation & purification MH - Sequence Analysis, DNA MH - Shrews/*virology MH - Vietnam/epidemiology EDAT- 2012/06/08 06:00 MHDA- 2013/03/07 06:00 CRDT- 2012/06/08 06:00 PHST- 2012/06/08 06:00 [entrez] PHST- 2012/06/08 06:00 [pubmed] PHST- 2013/03/07 06:00 [medline] AID - DN/JST.JSTAGE/jvms/11-0567 [pii] AID - 10.1292/jvms.11-0567 [doi] PST - ppublish SO - J Vet Med Sci. 2012 Sep;74(9):1155-62. doi: 10.1292/jvms.11-0567. Epub 2012 May 22.