PMID- 22673809
OWN - NLM
STAT- MEDLINE
DCOM- 20120904
LR  - 20120626
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1247
DP  - 2012 Jul 20
TI  - Solid-phase extraction combined with large volume injection-programmable 
      temperature vaporization-gas chromatography-mass spectrometry for the 
      multiresidue determination of priority and emerging organic pollutants in 
      wastewater.
PG  - 104-17
LID - 10.1016/j.chroma.2012.05.022 [doi]
AB  - In the present work the simultaneous extraction for the multiresidue 
      determination in wastewater samples of organic compounds such as polychlorinated 
      biphenyls (PCBs), polybrominated biphenyls (PBBs), pesticides, polycyclic 
      aromatic hydrocarbons (PAHs), phthalate esters (PEs), alkylphenols (APs), 
      bisphenol A (BPA) or hormones included in different lists of priority and 
      emerging pollutants because of their action as endocrine disrupting compounds 
      (EDCs) was developed. Different solid phase extraction (SPE) variables such as 
      the nature of the solid phase (Oasis-HLC, C18 and Lichrolut), the sample volume, 
      the addition of MeOH and NaCl, the pH of the water phase and the volume of the 
      eluent solvent were optimized in order to analyze simultaneously the priority and 
      emerging families of pollutants mentioned above. Good recoveries were obtained 
      for Milli-Q water (80-120%), however, since the use of deuterated analogues and 
      dilution of the sample did not correct the matrix effect, additional SPE clean-up 
      step using Florisil(R) cartridges was necessary to obtain good results for 
      wastewater samples (80-125%). In order to improve the limits of detection (LODs), 
      large volume injection (LVI) using programmable temperature vaporizer (PTV) 
      coupled to gas chromatography-mass spectrometry (GC-MS) was also optimized. Since 
      analytes losses in the case of the most volatile congeners occurred during the 
      derivatization step and no separation of the derivatized and the non-derivatized 
      analytes was possible during SPE elution, two different injections were optimized 
      for each analyte group. LODs were in good agreement with those found in the 
      literature and relative standard deviations (RSDs) were in the 10-25% range for 
      Milli-Q and 12-30% for wastewater samples. The method was finally applied to the 
      determination of target analytes in three different wastewater treatment plants 
      (WWTPs, Bakio, Gernika and Galindo (Spain)) and in one water purification plant 
      (WPP) in Zornotza (Spain).
CI  - Copyright (c) 2012 Elsevier B.V. All rights reserved.
FAU - Bizkarguenaga, E
AU  - Bizkarguenaga E
AD  - Department of Analytical Chemistry, Faculty of Science and Technology, University 
      of the Basque Country-UPV/EHU, PK 644, 48080 Bilbao, Spain.
FAU - Ros, O
AU  - Ros O
FAU - Iparraguirre, A
AU  - Iparraguirre A
FAU - Navarro, P
AU  - Navarro P
FAU - Vallejo, A
AU  - Vallejo A
FAU - Usobiaga, A
AU  - Usobiaga A
FAU - Zuloaga, O
AU  - Zuloaga O
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120514
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Organic Chemicals)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Limit of Detection
MH  - Organic Chemicals/*analysis/chemistry/isolation & purification
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Temperature
MH  - Waste Disposal, Fluid/*methods
MH  - Water Pollutants, Chemical/*analysis/chemistry/isolation & purification
MH  - Water Purification
EDAT- 2012/06/08 06:00
MHDA- 2012/09/05 06:00
CRDT- 2012/06/08 06:00
PHST- 2012/02/27 00:00 [received]
PHST- 2012/04/16 00:00 [revised]
PHST- 2012/05/06 00:00 [accepted]
PHST- 2012/06/08 06:00 [entrez]
PHST- 2012/06/08 06:00 [pubmed]
PHST- 2012/09/05 06:00 [medline]
AID - S0021-9673(12)00724-8 [pii]
AID - 10.1016/j.chroma.2012.05.022 [doi]
PST - ppublish
SO  - J Chromatogr A. 2012 Jul 20;1247:104-17. doi: 10.1016/j.chroma.2012.05.022. Epub 
      2012 May 14.