PMID- 22679788
OWN - NLM
STAT- MEDLINE
DCOM- 20120731
LR  - 20120611
IS  - 0016-6758 (Print)
IS  - 0016-6758 (Linking)
VI  - 48
IP  - 3
DP  - 2012 Mar
TI  - No association between the G196A and C270T polymorphism of the brain-derived 
      neurotrophic factor gene and male infertility.
PG  - 405-7
AB  - Brain-derived neurotrophic factor (BDNF) plays important roles in neuronal 
      development and reproductive action. Abnormal expression of BDNF gene has been 
      detected in human sperm and seminal serum. In the present study, we investigated 
      the possible association of G196A and C270T polymorphism of BDNF gene with male 
      infertility. The genotypes of the G196A and C270T polymorphisms were in 
      Hardy-Weinberg equilibrium both in fertile and infertile group. The genotype 
      distribution frequencies were similar between infertile and fertile group. The 
      results showed that the G196A and C270T polymorphism of the BDNF gene is 
      unrelated to the male infertility, at least in a Chinese population.
FAU - Li, Ch
AU  - Li Ch
AD  - College of Animal Science and Veterinary Medicine, Jilin Provincial Key 
      Laboratory of Animal Embryo Engineering, Jilin University, Changchun, Jilin 
      Province 130062, China.
FAU - Zheng, L
AU  - Zheng L
FAU - Sun, Y
AU  - Sun Y
FAU - Wang, Ch
AU  - Wang Ch
FAU - Li, W
AU  - Li W
FAU - Lu, Ch
AU  - Lu Ch
FAU - Zhou, X
AU  - Zhou X
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Russia (Federation)
TA  - Genetika
JT  - Genetika
JID - 0047354
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adult
MH  - Brain-Derived Neurotrophic Factor/*genetics
MH  - China
MH  - Genetic Association Studies
MH  - Genotype
MH  - Humans
MH  - Infertility, Male/*genetics
MH  - Male
MH  - Polymorphism, Genetic
EDAT- 2012/06/12 06:00
MHDA- 2012/08/01 06:00
CRDT- 2012/06/12 06:00
PHST- 2012/06/12 06:00 [entrez]
PHST- 2012/06/12 06:00 [pubmed]
PHST- 2012/08/01 06:00 [medline]
PST - ppublish
SO  - Genetika. 2012 Mar;48(3):405-7.