PMID- 22686510 OWN - NLM STAT- MEDLINE DCOM- 20130131 LR - 20211021 IS - 1756-0500 (Electronic) IS - 1756-0500 (Linking) VI - 5 DP - 2012 Jun 11 TI - Prevalence of a marker of active helicobacter pylori infection among patients with type 2 diabetes mellitus in Lagos, Nigeria. PG - 284 LID - 10.1186/1756-0500-5-284 [doi] AB - BACKGROUND: There appears to exist a potentially important interplay between diabetes mellitus (DM) and Helicobacter pylori (H. pylori) infection. Findings from previous studies have been conflicting. Only a few studies have examined the topic in a sub-Saharan African population. This study sought to determine the prevalence of H. pylori infection among Type 2 diabetes mellitus (T2DM) patients in Lagos, Nigeria. FINDINGS: H. pylori infection was detected in 18% of T2DM patients and 13% of controls but there was no statistical significance in this difference (p = 0.52). The prevalence of H. pylori was neither associated with the known duration of T2DM nor was it associated with age, gender, body mass index (BMI), smoking status. T2DM was not shown to be a risk factor independently associated with risk for H. pylori infection (OR = 0.87, 95% CI = 0.58-1.31, p = 0.57). CONCLUSIONS: The lack of a statistical significant difference between the H. pylori infection rates in T2DM patients and controls suggests that the infection is not increased in T2DM. Larger studies need to be conducted to confirm the study findings. FAU - Oluyemi, Aderemi AU - Oluyemi A AD - General Hospital, Ikorodu, Lagos State, Nigeria. remioluyemi@yahoo.com FAU - Anomneze, Ebere AU - Anomneze E FAU - Smith, Stella AU - Smith S FAU - Fasanmade, Olufemi AU - Fasanmade O LA - eng PT - Journal Article DEP - 20120611 PL - England TA - BMC Res Notes JT - BMC research notes JID - 101462768 RN - 0 (Antigens, Bacterial) RN - 0 (Biomarkers) RN - 0 (Blood Glucose) SB - IM MH - Aged MH - Antigens, Bacterial/isolation & purification MH - Biomarkers/blood MH - Blood Glucose/analysis MH - Case-Control Studies MH - Chi-Square Distribution MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/blood/diagnosis/*epidemiology MH - Feces/microbiology MH - Female MH - Helicobacter Infections/diagnosis/*epidemiology/microbiology MH - Helicobacter pylori/immunology/*isolation & purification MH - Humans MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Nigeria/epidemiology MH - Odds Ratio MH - Prevalence MH - Risk Assessment MH - Risk Factors PMC - PMC3433385 EDAT- 2012/06/13 06:00 MHDA- 2013/02/01 06:00 PMCR- 2012/06/11 CRDT- 2012/06/13 06:00 PHST- 2011/11/18 00:00 [received] PHST- 2012/06/01 00:00 [accepted] PHST- 2012/06/13 06:00 [entrez] PHST- 2012/06/13 06:00 [pubmed] PHST- 2013/02/01 06:00 [medline] PHST- 2012/06/11 00:00 [pmc-release] AID - 1756-0500-5-284 [pii] AID - 10.1186/1756-0500-5-284 [doi] PST - epublish SO - BMC Res Notes. 2012 Jun 11;5:284. doi: 10.1186/1756-0500-5-284.