PMID- 22693239
OWN - NLM
STAT- MEDLINE
DCOM- 20121018
LR  - 20191112
IS  - 1543-2742 (Electronic)
IS  - 1526-484X (Linking)
VI  - 22
IP  - 3
DP  - 2012 Jun
TI  - The effects of postexercise feeding on saliva antimicrobial proteins.
PG  - 184-91
AB  - The purpose of this study was to determine the effects of a carbohydrate (CHO) 
      and protein (PRO) drink consumed immediately after endurance exercise on saliva 
      antimicrobial proteins known to be important for host defense. Eleven male 
      runners ran for 2 hr at 75% VO2max on 2 occasions and immediately postexercise 
      were provided, in randomized order, either a placebo solution (CON) or a CHO-PRO 
      solution containing 1.2 g CHO/kg body mass (BM) and 0.4 g PRO/kg BM (CHO-PRO). 
      The solutions were flavor and volume equivalent (12 ml/kg BM). Saliva flow rate, 
      lysozyme, alpha-amylase, and secretory (S) IgA concentrations were determined from 
      unstimulated saliva samples collected preexercise, immediately postexercise, and 
      every 30 min until 180 min postexercise. CHO-PRO ingestion immediately 
      postexercise resulted in a lower saliva flow rate than with CON at 30 and 60 min 
      postexercise. Saliva lysozyme concentration increased immediately postexercise in 
      both trials compared with preexercise (p< .05), and CHO-PRO ingestion immediately 
      postexercise resulted in a higher saliva lysozyme concentration in the first hour 
      of recovery than with CON (125% greater at 30 min, 94% greater at 60 min; p< 
      .01). Saliva SIgA concentration decreased below preexercise concentrations 90-150 
      min postexercise (p< .001), with no effect of CHO-PRO. Saliva alpha-amylase activity 
      was unaffected by exercise or CHO-PRO refeeding. CHO-PRO refeeding did not alter 
      the secretion rates of any saliva variables during recovery. In conclusion, 
      immediate refeeding with CHO-PRO evoked a greater saliva lysozyme concentration 
      during the first hour of recovery after prolonged exercise than ingestion of 
      placebo but had minimal impact on saliva alpha-amylase and SIgA responses.
FAU - Costa, Ricardo J S
AU  - Costa RJ
AD  - Dept. of Physiotherapy and Dietetics, Coventry University, Coventry, UK.
FAU - Fortes, Matthew B
AU  - Fortes MB
FAU - Richardson, Katharine
AU  - Richardson K
FAU - Bilzon, James L J
AU  - Bilzon JL
FAU - Walsh, Neil P
AU  - Walsh NP
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Biological Factors)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Immunoglobulin A)
RN  - 0 (Salivary Proteins and Peptides)
RN  - EC 3.2.1.1 (alpha-Amylases)
RN  - EC 3.2.1.17 (Muramidase)
SB  - IM
MH  - Adult
MH  - Anti-Infective Agents
MH  - Biological Factors/*metabolism
MH  - Diet
MH  - Dietary Carbohydrates/*pharmacology
MH  - Dietary Proteins/*pharmacology
MH  - Feeding Behavior/physiology
MH  - Humans
MH  - Immunoglobulin A/metabolism
MH  - Male
MH  - Muramidase/*metabolism
MH  - Oxygen Consumption
MH  - Running/*physiology
MH  - Saliva/metabolism/*physiology
MH  - Salivary Proteins and Peptides/*metabolism
MH  - Young Adult
MH  - alpha-Amylases/metabolism
EDAT- 2012/06/14 06:00
MHDA- 2012/10/19 06:00
CRDT- 2012/06/14 06:00
PHST- 2012/06/14 06:00 [entrez]
PHST- 2012/06/14 06:00 [pubmed]
PHST- 2012/10/19 06:00 [medline]
AID - 10.1123/ijsnem.22.3.184 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2012 Jun;22(3):184-91. doi: 
      10.1123/ijsnem.22.3.184.