PMID- 22695250 OWN - NLM STAT- MEDLINE DCOM- 20130124 LR - 20211021 IS - 1476-511X (Electronic) IS - 1476-511X (Linking) VI - 11 DP - 2012 Jun 13 TI - Automated diagnosis of diabetic retinopathy and glaucoma using fundus and OCT images. PG - 73 LID - 10.1186/1476-511X-11-73 [doi] AB - We describe a system for the automated diagnosis of diabetic retinopathy and glaucoma using fundus and optical coherence tomography (OCT) images. Automatic screening will help the doctors to quickly identify the condition of the patient in a more accurate way. The macular abnormalities caused due to diabetic retinopathy can be detected by applying morphological operations, filters and thresholds on the fundus images of the patient. Early detection of glaucoma is done by estimating the Retinal Nerve Fiber Layer (RNFL) thickness from the OCT images of the patient. The RNFL thickness estimation involves the use of active contours based deformable snake algorithm for segmentation of the anterior and posterior boundaries of the retinal nerve fiber layer. The algorithm was tested on a set of 89 fundus images of which 85 were found to have at least mild retinopathy and OCT images of 31 patients out of which 13 were found to be glaucomatous. The accuracy for optical disk detection is found to be 97.75%. The proposed system therefore is accurate, reliable and robust and can be realized. FAU - Pachiyappan, Arulmozhivarman AU - Pachiyappan A AD - School of Electronics Engineering, VIT University, Vellore 632014 Tamil Nadu, India. FAU - Das, Undurti N AU - Das UN FAU - Murthy, Tatavarti Vsp AU - Murthy TV FAU - Tatavarti, Rao AU - Tatavarti R LA - eng PT - Journal Article DEP - 20120613 PL - England TA - Lipids Health Dis JT - Lipids in health and disease JID - 101147696 SB - IM MH - Aneurysm/diagnosis MH - Automation, Laboratory MH - Diabetic Retinopathy/*diagnosis MH - *Fundus Oculi MH - Glaucoma/*diagnosis MH - Humans MH - Retinal Hemorrhage/diagnosis MH - Retinal Vessels/pathology MH - *Tomography, Optical Coherence PMC - PMC3477058 EDAT- 2012/06/15 06:00 MHDA- 2013/01/25 06:00 PMCR- 2012/06/13 CRDT- 2012/06/15 06:00 PHST- 2012/04/23 00:00 [received] PHST- 2012/05/11 00:00 [accepted] PHST- 2012/06/15 06:00 [entrez] PHST- 2012/06/15 06:00 [pubmed] PHST- 2013/01/25 06:00 [medline] PHST- 2012/06/13 00:00 [pmc-release] AID - 1476-511X-11-73 [pii] AID - 10.1186/1476-511X-11-73 [doi] PST - epublish SO - Lipids Health Dis. 2012 Jun 13;11:73. doi: 10.1186/1476-511X-11-73.