PMID- 22696365
OWN - NLM
STAT- MEDLINE
DCOM- 20120813
LR  - 20220330
IS  - 1469-493X (Electronic)
IS  - 1361-6137 (Linking)
VI  - 2012
IP  - 6
DP  - 2012 Jun 13
TI  - Photorefractive keratectomy (PRK) versus laser assisted in situ keratomileusis 
      (LASIK) for hyperopia correction.
PG  - CD007112
LID - 10.1002/14651858.CD007112.pub3 [doi]
LID - CD007112
AB  - BACKGROUND: Hyperopia, or hypermetropia (also known as long-sightedness or 
      far-sightedness), is the condition where the unaccommodating eye brings parallel 
      light to a focus behind the retina instead of on it. Hyperopia can be corrected 
      with both non-surgical and surgical methods, among them photorefractive 
      keratectomy (PRK) and laser assisted In situ keratomileusis (LASIK). There is 
      uncertainty as to whether hyperopic-PRK or hyperopic-LASIK is the better method. 
      OBJECTIVES: The objectives of this review were to determine whether PRK or LASIK 
      leads to more reliable, stable and safe results when correcting a hyperopic 
      refractive error. SEARCH METHODS: We searched CENTRAL (which contains the 
      Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2012, Issue 
      2), MEDLINE (January 1950 to February 2012), EMBASE (January 1980 to February 
      2012), Latin American and Caribbean Literature on Health Sciences (LILACS) 
      (January 1982 to February 2012), the metaRegister of Controlled Trials (mRCT) 
      (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the 
      WHO International Clinical Trials Registry Platform (ICTRP) 
      (www.who.int/ictrp/search/en). There were no date or language restrictions in the 
      electronic searches for trials. The electronic databases were last searched on 17 
      February 2012. When trials are included in the review we will search the 
      reference lists of the studies included in the review for information about 
      further trials. We will use the Science Citation Index to search for papers that 
      cite any studies included in this review. We did not handsearch journals or 
      conference proceedings specifically for this review. SELECTION CRITERIA: We 
      planned to include only randomised controlled trials (RCTs) comparing PRK against 
      LASIK for correction of hyperopia and then perform a sensitivity analysis of pre- 
      and post-millennial trials since this is the mid-point in the history of both PRK 
      and LASIK. DATA COLLECTION AND ANALYSIS: We did not identify any studies that met 
      the inclusion criteria for this review. MAIN RESULTS: As no studies met the 
      inclusion criteria for this review, we discussed the results of non-randomised 
      trials comparing hyperopic-PRK with hyperopic-LASIK. AUTHORS' CONCLUSIONS: No 
      robust, reliable conclusions could be reached, but the non-randomised trials 
      reviewed appear to be in agreement that hyperopic-PRK and hyperopic-LASIK are of 
      comparable efficacy. High quality, well-planned open RCTs are needed in order to 
      obtain a robust clinical evidence base.
FAU - Settas, George
AU  - Settas G
AD  - Optimax plc, London, UK. 2Fitzwilliam Hospital, Peterborough, 
      UK.settasg@doctors.org.uk.
FAU - Settas, Clare
AU  - Settas C
FAU - Minos, Evangelos
AU  - Minos E
FAU - Yeung, Ian Yl
AU  - Yeung IY
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
DEP - 20120613
PL  - England
TA  - Cochrane Database Syst Rev
JT  - The Cochrane database of systematic reviews
JID - 100909747
SB  - IM
UOF - Cochrane Database Syst Rev. 2009;(2):CD007112. PMID: 19370672
MH  - Humans
MH  - Hyperopia/*surgery
MH  - *Keratomileusis, Laser In Situ
MH  - *Photorefractive Keratectomy
PMC - PMC7388917
COIS- None known.
EDAT- 2012/06/15 06:00
MHDA- 2012/08/14 06:00
PMCR- 2013/06/13
CRDT- 2012/06/15 06:00
PHST- 2012/06/15 06:00 [entrez]
PHST- 2012/06/15 06:00 [pubmed]
PHST- 2012/08/14 06:00 [medline]
PHST- 2013/06/13 00:00 [pmc-release]
AID - CD007112.pub3 [pii]
AID - 10.1002/14651858.CD007112.pub3 [doi]
PST - epublish
SO  - Cochrane Database Syst Rev. 2012 Jun 13;2012(6):CD007112. doi: 
      10.1002/14651858.CD007112.pub3.