PMID- 22710476 OWN - NLM STAT- Publisher LR - 20240227 IS - 1543-2742 (Electronic) IS - 1526-484X (Linking) DP - 2012 Jun 15 TI - The effects of post-exercise feeding on saliva anti-microbial proteins. AB - The purpose was to determine the effects of a carbohydrate (CHO)-protein (PRO) drink, consumed immediately after endurance exercise on saliva anti-microbial proteins known to be important for host defence. Eleven male runners ran for 2 h at 75% VO2max on two occasions, and immediately post-exercise were provided, in randomised order, either a placebo solution (CON), or a CHO-PRO solution containing 1.2 gCHO.kg-1BM and 0.4 gPRO.kg-1BM (CHO-PRO). Both solutions were flavour and volume equivalent (12 ml.kg- 1BM). Saliva flow rate, lysozyme, alpha-amylase, and secretory (S) IgA concentrations were determined from unstimulated saliva samples collected pre-exercise, immediately post-exercise and every 30 min until 180 min post-exercise. CHO-PRO ingestion immediately post-exercise resulted in a lower saliva flow rate compared with CON at 30 and 60 min post exercise. Saliva lysozyme concentration increased immediately post-exercise in both trials compared with pre-exercise (P< 0.05), and CHO-PRO ingestion immediately post-exercise resulted in a higher saliva lysozyme concentration in the first hour of recovery compared with CON (125% greater at 30 min; 94% greater at 60 min, P< 0.01). Saliva SIgA concentration decreased below pre-exercise concentrations 90-150 min post-exercise (P< 0.01) with no effect of CHO-PRO. Saliva alpha-amylase activity was unaffected by exercise or CHO-PRO re-feeding. CHO-PRO re-feeding did not alter the secretion rates of any saliva variables during recovery. In conclusion, immediate re-feeding with CHO-PRO evoked a greater saliva lysozyme concentration during the first hour of recovery after prolonged exercise compared with ingestion of placebo, but had minimal impact upon saliva alpha-amylase and SIgA responses. FAU - Costa R, J S AU - Costa R JS AD - Department of Physiotherapy and Dietetics, Coventry University, Coventry, UK. FAU - Fortes, Matthew B AU - Fortes MB FAU - Richardson, Katharine AU - Richardson K FAU - Bilzon J, L J AU - Bilzon J LJ FAU - Walsh, Neil P AU - Walsh NP LA - eng PT - Journal Article DEP - 20120615 PL - United States TA - Int J Sport Nutr Exerc Metab JT - International journal of sport nutrition and exercise metabolism JID - 100939812 EDAT- 2012/06/20 06:00 MHDA- 2012/06/20 06:00 CRDT- 2012/06/20 06:00 PHST- 2012/06/20 06:00 [entrez] PHST- 2012/06/20 06:00 [pubmed] PHST- 2012/06/20 06:00 [medline] AID - 2011-0169 [pii] PST - aheadofprint SO - Int J Sport Nutr Exerc Metab. 2012 Jun 15.