PMID- 22712038 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211021 IS - 1939-5086 (Electronic) IS - 1939-5078 (Print) IS - 1939-5078 (Linking) VI - 3 IP - 4 DP - 2012 Jul TI - The representation of self and person knowledge in the medial prefrontal cortex. PG - 451-470 LID - 10.1002/wcs.1183 [doi] AB - Nearly 40 years ago, social psychologists began applying the information processing framework of cognitive psychology to the question of how humans understand and represent knowledge about themselves and others. This approach gave rise to the immensely successful field of social cognition and fundamentally changed the way in which social psychological phenomena are studied. More recently, social scientists of many stripes have turned to the methods of cognitive neuroscience to understand the neural basis of social cognition. A pervasive finding from this research is that social knowledge, be it about one's self or of others, is represented in the medial prefrontal cortex (MPFC). This review focuses on the social cognitive neuroscience of self and person knowledge in the MPFC. We begin with a brief historical overview of social cognition, followed by a review of recent and influential research on the brain basis of self and person knowledge. In the latter half of this review, we discuss the role of familiarity and similarity in person perception and of spontaneous processes in self and other-referential cognition. Throughout, we discuss the myriad ways in which the social cognitive neuroscience approach has provided new insights into the nature and structure of self and person knowledge. WIREs Cogn Sci 2012, 3:451-470. doi: 10.1002/wcs.1183 This article is categorized under: Neuroscience > Cognition. CI - Copyright (c) 2012 John Wiley & Sons, Ltd. FAU - Wagner, Dylan D AU - Wagner DD AD - Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH, USA. FAU - Haxby, James V AU - Haxby JV AD - Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH, USA. FAU - Heatherton, Todd F AU - Heatherton TF AD - Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH, USA. LA - eng GR - R01 MH059282/MH/NIMH NIH HHS/United States GR - R01 MH059282-10/MH/NIMH NIH HHS/United States PT - Journal Article PT - Review DEP - 20120507 PL - United States TA - Wiley Interdiscip Rev Cogn Sci JT - Wiley interdisciplinary reviews. Cognitive science JID - 101524169 PMC - PMC3375705 MID - NIHMS371019 EDAT- 2012/06/20 06:00 MHDA- 2012/06/20 06:01 PMCR- 2013/05/07 CRDT- 2012/06/20 06:00 PHST- 2012/06/20 06:00 [pubmed] PHST- 2012/06/20 06:01 [medline] PHST- 2012/06/20 06:00 [entrez] PHST- 2013/05/07 00:00 [pmc-release] AID - 10.1002/wcs.1183 [doi] PST - ppublish SO - Wiley Interdiscip Rev Cogn Sci. 2012 Jul;3(4):451-470. doi: 10.1002/wcs.1183. Epub 2012 May 7.