PMID- 22715692
OWN - NLM
STAT- MEDLINE
DCOM- 20140730
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 3
DP  - 2012 Mar
TI  - [Rapid determination of 40 pesticide residues in fruits using gas 
      chromatography-mass spectrometry coupled with analyte protectants to compensate 
      for matrix effects].
PG  - 267-72
AB  - A gas chromatography-mass spectrometry (GC-MS) method was developed for the 
      determination of 40 pesticides in fruits. The effects of adding analyte 
      protectants were evaluated for compensating matrix effects and the impacts on the 
      quantitative results. A new combination of analyte protectants - Polyethylene 
      Glycol 400 (PEG 400) and olive oil combination, which can be dissolved in 
      acetone, was used for the quantitative analysis. The pesticides were extracted 
      from fruit samples with acetonitrile and the extracts were cleaned up using 
      micro-solid phase extraction. A GC-MS method in selective ion monitoring (SIM) 
      mode coupled with large volume injection was finally developed. Using the newly 
      developed analyte protectant combination of PEG 400 and olive oil, a good 
      linearity was obtained in the range of 1 - 200 microg/L with coefficients better 
      than 0.99, and the detection limits were between 0.1 - 3.0 microg/L. The mean 
      recoveries of the pesticides were 75% - 119% with the relative standard deviation 
      values less than 16.6% except for dimethoate. The performance of the analyte 
      protectants was compared with matrix-matched standards calibration curves in 
      terms of quantitative accuracy. The results showed that the method of adding 
      analyte protectants can replace the matrix-matched standard calibration, and can 
      also reduce the sample pretreatment. When the devel- oped method was used for the 
      analysis of apple, peache, orange, banana, grape and other fruit samples, a good 
      matrix compensation effect was achieved, and thus effectively reduced the bad 
      effects of the water-soluble agents to the gas chromatographic column.
FAU - Xu, Xiuli
AU  - Xu X
AD  - Chinese Academy of Inspection and Quarantine, Beijing 100123, China.
FAU - Zhao, Haixiang
AU  - Zhao H
FAU - Li, Li
AU  - Li L
FAU - Liu, Hanxia
AU  - Liu H
FAU - Ren, Heling
AU  - Ren H
FAU - Zhong, Weike
AU  - Zhong W
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Olive Oil)
RN  - 0 (Pesticide Residues)
RN  - 0 (Plant Oils)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
SB  - IM
MH  - Food Contamination/analysis
MH  - Fruit/*chemistry
MH  - *Gas Chromatography-Mass Spectrometry
MH  - Olive Oil
MH  - Pesticide Residues/*analysis
MH  - Plant Oils/chemistry
MH  - Polyethylene Glycols/chemistry
EDAT- 2012/06/22 06:00
MHDA- 2014/07/31 06:00
CRDT- 2012/06/22 06:00
PHST- 2012/06/22 06:00 [entrez]
PHST- 2012/06/22 06:00 [pubmed]
PHST- 2014/07/31 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.11008 [doi]
PST - ppublish
SO  - Se Pu. 2012 Mar;30(3):267-72. doi: 10.3724/sp.j.1123.2011.11008.