PMID- 22722754 OWN - NLM STAT- MEDLINE DCOM- 20130524 LR - 20211021 IS - 1618-727X (Electronic) IS - 0897-1889 (Print) IS - 0897-1889 (Linking) VI - 25 IP - 6 DP - 2012 Dec TI - Extreme compression for extreme conditions: pilot study to identify optimal compression of CT images using MPEG-4 video compression. PG - 764-70 LID - 10.1007/s10278-012-9500-8 [doi] AB - This study aims to evaluate the utility of compressed computed tomography (CT) studies (to expedite transmission) using Motion Pictures Experts Group, Layer 4 (MPEG-4) movie formatting in combat hospitals when guiding major treatment regimens. This retrospective analysis was approved by Walter Reed Army Medical Center institutional review board with a waiver for the informed consent requirement. Twenty-five CT chest, abdomen, and pelvis exams were converted from Digital Imaging and Communications in Medicine to MPEG-4 movie format at various compression ratios. Three board-certified radiologists reviewed various levels of compression on emergent CT findings on 25 combat casualties and compared with the interpretation of the original series. A Universal Trauma Window was selected at -200 HU level and 1,500 HU width, then compressed at three lossy levels. Sensitivities and specificities for each reviewer were calculated along with 95 % confidence intervals using the method of general estimating equations. The compression ratios compared were 171:1, 86:1, and 41:1 with combined sensitivities of 90 % (95 % confidence interval, 79-95), 94 % (87-97), and 100 % (93-100), respectively. Combined specificities were 100 % (85-100), 100 % (85-100), and 96 % (78-99), respectively. The introduction of CT in combat hospitals with increasing detectors and image data in recent military operations has increased the need for effective teleradiology; mandating compression technology. Image compression is currently used to transmit images from combat hospital to tertiary care centers with subspecialists and our study demonstrates MPEG-4 technology as a reasonable means of achieving such compression. FAU - Peterson, P Gabriel AU - Peterson PG AD - Walter Reed National Military Medical Center, Bethesda, MD 20889-5600, USA. FAU - Pak, Sung K AU - Pak SK FAU - Nguyen, Binh AU - Nguyen B FAU - Jacobs, Genevieve AU - Jacobs G FAU - Folio, Les AU - Folio L LA - eng PT - Journal Article PL - United States TA - J Digit Imaging JT - Journal of digital imaging JID - 9100529 SB - IM MH - Adult MH - Data Compression/*methods MH - Female MH - Humans MH - Male MH - *Military Personnel MH - Pilot Projects MH - ROC Curve MH - Radiographic Image Interpretation, Computer-Assisted MH - Retrospective Studies MH - Sensitivity and Specificity MH - *Tomography, X-Ray Computed MH - Wounds and Injuries/*diagnostic imaging PMC - PMC3491159 EDAT- 2012/06/23 06:00 MHDA- 2013/05/28 06:00 PMCR- 2013/12/01 CRDT- 2012/06/23 06:00 PHST- 2012/06/23 06:00 [entrez] PHST- 2012/06/23 06:00 [pubmed] PHST- 2013/05/28 06:00 [medline] PHST- 2013/12/01 00:00 [pmc-release] AID - 9500 [pii] AID - 10.1007/s10278-012-9500-8 [doi] PST - ppublish SO - J Digit Imaging. 2012 Dec;25(6):764-70. doi: 10.1007/s10278-012-9500-8.