PMID- 22726409
OWN - NLM
STAT- MEDLINE
DCOM- 20121212
LR  - 20151119
IS  - 0013-7006 (Print)
IS  - 0013-7006 (Linking)
VI  - 38
IP  - 3
DP  - 2012 Jun
TI  - [Who are patients suffering from bipolar disorders in France? The TEMPPO survey: 
      patients' sociodemographic and clinical characteristics data].
PG  - 211-23
LID - 10.1016/j.encep.2012.04.007 [doi]
AB  - AIM: One of the aims of the TEMPPO study was to describe the sociodemographic and 
      clinical characteristics of a cohort of adult outpatients with type I or type II 
      bipolar disorders (as defined by DSM-IV criteria) in France. METHODS: TEMPPO is a 
      multicenter, cross-sectional, non-interventional study conducted in France 
      between November 2008 and May 2009, with a random sample of academic and private 
      practice psychiatrists. Each psychiatrist who agreed to participate in the study 
      had to: complete a register with data on all consecutive patients (up to 20 
      patients) consulting during a 2-month period and fulfilling inclusion criteria; 
      include in the study the first five patients of the register with an on-going 
      consultation for at least 6 months; for each of which a detailed questionnaire 
      had been assessed, notably their sociodemographic and bipolar clinical 
      characteristics. Adult outpatients diagnosed with bipolar disorders (BD) were 
      enrolled if fulfilling the following inclusion criteria: man or woman, aged 18 
      and above, diagnosed bipolar type I or II according to DSM-IV criteria, treated 
      (whatever the treatment strategy) or not, and followed-up for at least 6 months 
      by the participating psychiatrist. RESULTS: One hundred and thirty-five 
      psychiatrists included 619 patients with bipolar disorder (197 and 422 
      followed-up in public and private practice respectively). The estimated 
      prevalence of patients with bipolar disorders consulting psychiatrists was 0.43%. 
      Type I bipolar disorder was the most frequent condition (58% of the patients). As 
      a whole, bipolar disorder was associated with severe handicap (mean global 
      disease Clinical Global Impression [CGI]-Severity score of 4.4 and mean GAF 
      [Global Assessment of Functioning] score of 59), with more depressive episodes 
      than manic episodes (6 vs. 4) or hypomania (6 vs. 3), a high proportion of rapid 
      cycles (11%), psychiatric comorbidities (45% of patients), obesity (16% of 
      patients), libido dysfunction and associated psychotic symptoms. Current manic 
      phase was associated with more pronounced illness severity and lowest 
      functioning. More than half of the patients (57%) had a family history of 
      psychiatric disorders. CONCLUSION: This study could shed some light for a better 
      understanding of demographics and clinical patterns of patients with bipolar 
      disorders consulting psychiatrists in France. The results emphasize the severity 
      of bipolar disorders with mainly depressive episodes, a high proportion of 
      rapid-cycling, comorbidities and associated psychotic symptoms; these 
      characteristics being more marked in patients suffering from BD I. Furthermore, 
      this study confirms the strong negative impact on social and professional life of 
      French bipolar patients, requiring specific management in addition to the 
      symptomatic treatment.
CI  - Copyright (c) 2012 L'Encephale, Paris. Published by Elsevier Masson SAS. All rights 
      reserved.
FAU - de Carvalho, W
AU  - de Carvalho W
AD  - Maison de sante de Bellevue, 8, avenue du 11-Novembre-1918, 92190 Meudon, France. 
      wd.decarvalho@wanadoo.fr
FAU - Nuss, P
AU  - Nuss P
FAU - Blin, P
AU  - Blin P
FAU - Arnaud, R
AU  - Arnaud R
FAU - Filipovics, A
AU  - Filipovics A
FAU - Loze, J-Y
AU  - Loze JY
FAU - Dillenschneider, A
AU  - Dillenschneider A
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Caracteristiques sociodemographiques et cliniques de patients souffrant de 
      troubles bipolaires suivis en ambulatoire en France metropolitaine.
DEP - 20120605
PL  - France
TA  - Encephale
JT  - L'Encephale
JID - 7505643
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Ambulatory Care/*statistics & numerical data
MH  - Antipsychotic Agents/therapeutic use
MH  - Bipolar Disorder/diagnosis/drug therapy/*epidemiology/psychology
MH  - Cohort Studies
MH  - Cross-Sectional Studies
MH  - Drug Utilization
MH  - Female
MH  - Follow-Up Studies
MH  - France
MH  - Health Surveys
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Practice Patterns, Physicians'/statistics & numerical data
MH  - Psychiatric Status Rating Scales
MH  - Social Adjustment
MH  - Socioeconomic Factors
EDAT- 2012/06/26 06:00
MHDA- 2012/12/13 06:00
CRDT- 2012/06/26 06:00
PHST- 2011/06/21 00:00 [received]
PHST- 2012/04/06 00:00 [accepted]
PHST- 2012/06/26 06:00 [entrez]
PHST- 2012/06/26 06:00 [pubmed]
PHST- 2012/12/13 06:00 [medline]
AID - S0013-7006(12)00073-5 [pii]
AID - 10.1016/j.encep.2012.04.007 [doi]
PST - ppublish
SO  - Encephale. 2012 Jun;38(3):211-23. doi: 10.1016/j.encep.2012.04.007. Epub 2012 Jun 
      5.