PMID- 22754642 OWN - NLM STAT- MEDLINE DCOM- 20121024 LR - 20211021 IS - 1999-4915 (Electronic) IS - 1999-4915 (Linking) VI - 4 IP - 5 DP - 2012 May TI - Evaluation of the long-term effect of air filtration on the occurrence of new PRRSV infections in large breeding herds in swine-dense regions. PG - 654-62 LID - v4050654 [pii] LID - 10.3390/v4050654 [doi] AB - Airborne transmission of porcine reproductive and respiratory syndrome virus (PRRSV) is a risk factor for the infection of susceptible populations. Therefore, a long‑term sustainability study of air filtration as a means to reduce this risk was conducted. Participating herds (n = 38) were organized into 4 independent cohorts and the effect of air filtration on the occurrence of new PRRSV infections was analyzed at 3 different levels from September 2008 to January 2012 including the likelihood of infection in contemporary filtered and non-filtered herds, the likelihood of infection before and after implementation of filtration and the time to failure in filtered and non-filtered herds. Results indicated that new PRRSV infections in filtered breeding herds were significantly lower than in contemporary non-filtered control herds (P < 0.01), the odds for a new PRRSV infection in breeding herds before filtration was 7.97 times higher than the odds after filtration was initiated (P < 0.01) and the median time to new PRRSV infections in filtered breeding herds of 30 months was significantly longer than the 11 months observed in non-filtered herds (P < 0.01). In conclusion, across all 3 levels of analysis, the long-term effect of air filtration on reducing the occurrence of new PRRSV infections in the study population was demonstrated. FAU - Dee, Scott AU - Dee S AD - Pipestone Veterinary Clinic, Pipestone, MN 56164, USA. sdee@pipevet.com FAU - Cano, Jean Paul AU - Cano JP FAU - Spronk, Gordon AU - Spronk G FAU - Reicks, Darwin AU - Reicks D FAU - Ruen, Paul AU - Ruen P FAU - Pitkin, Andrea AU - Pitkin A FAU - Polson, Dale AU - Polson D LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. DEP - 20120426 PL - Switzerland TA - Viruses JT - Viruses JID - 101509722 SB - IM MH - *Air Microbiology MH - Animals MH - Disinfection/*methods MH - Filtration/*methods MH - Infection Control/*methods MH - Porcine Reproductive and Respiratory Syndrome/*prevention & control/transmission MH - Porcine respiratory and reproductive syndrome virus/*isolation & purification/pathogenicity MH - Swine MH - Time Factors PMC - PMC3386623 OTO - NOTNLM OT - air OT - breeding OT - filtration OT - herds OT - porcine OT - reproductive OT - respiratory OT - syndrome OT - virus EDAT- 2012/07/04 06:00 MHDA- 2012/10/25 06:00 PMCR- 2012/05/01 CRDT- 2012/07/04 06:00 PHST- 2012/03/20 00:00 [received] PHST- 2012/04/21 00:00 [revised] PHST- 2012/04/24 00:00 [accepted] PHST- 2012/07/04 06:00 [entrez] PHST- 2012/07/04 06:00 [pubmed] PHST- 2012/10/25 06:00 [medline] PHST- 2012/05/01 00:00 [pmc-release] AID - v4050654 [pii] AID - viruses-04-00654 [pii] AID - 10.3390/v4050654 [doi] PST - ppublish SO - Viruses. 2012 May;4(5):654-62. doi: 10.3390/v4050654. Epub 2012 Apr 26.