PMID- 22760961
OWN - NLM
STAT- MEDLINE
DCOM- 20130607
LR  - 20211021
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 251
IP  - 2
DP  - 2013 Feb
TI  - Spectral-domain optical coherence tomography detects optic atrophy due to optic 
      tract syndrome.
PG  - 591-5
LID - 10.1007/s00417-012-2096-3 [doi]
AB  - BACKGROUND: Unilateral injury of the optic tract leads to asymmetrical optic 
      atrophy in both eyes derived from the crossing of the nerve fibers at the chiasm. 
      This report demonstrates unique imaging appearances of optic atrophy due to this 
      uncommon condition detected by spectral-domain optical coherence tomography 
      (SD-OCT). METHODS: Cirrus and RTVue measurements were performed in four cases of 
      optic tract syndrome. Circumpapillary retinal nerve fiber layer (cpRNFL) 
      thickness was obtained from both instruments and ganglion cell complex (GCC) 
      integrity was obtained from RTVue. The presumable reduction rates of quadrant 
      cpRNFL thickness were calculated from the published normative database and 
      compared between eyes with temporal hemianopia and those with nasal hemianopia. 
      RESULTS: Both devices showed significant reduction of cpRNFL thickness, but did 
      not have statistical difference in the reduction rates at temporal or nasal 
      quadrant cpRNFL between contralateral and ipsilateral eyes to the lesion. 
      Color-coded maps helped to visualize the unique pattern of cpRNFL and GCC 
      thinning. CONCLUSIONS: SD-OCT can be used as a diagnostic tool for the optic 
      tract syndrome.
FAU - Kanamori, Akiyasu
AU  - Kanamori A
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, Japan. kanaaki@med.kobe-u.ac.jp
FAU - Nakamura, Makoto
AU  - Nakamura M
FAU - Yamada, Yuko
AU  - Yamada Y
FAU - Negi, Akira
AU  - Negi A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120704
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - Female
MH  - Hemianopsia/*diagnosis/etiology
MH  - Humans
MH  - Male
MH  - Nerve Fibers/*pathology
MH  - Optic Atrophy/*diagnosis/etiology
MH  - Pupil Disorders/*diagnosis/etiology
MH  - Retinal Ganglion Cells/*pathology
MH  - *Tomography, Optical Coherence
MH  - Visual Acuity
MH  - Visual Field Tests
MH  - Visual Fields
MH  - Visual Pathways/*pathology
MH  - Young Adult
EDAT- 2012/07/05 06:00
MHDA- 2013/06/08 06:00
CRDT- 2012/07/05 06:00
PHST- 2012/03/15 00:00 [received]
PHST- 2012/06/15 00:00 [accepted]
PHST- 2012/06/04 00:00 [revised]
PHST- 2012/07/05 06:00 [entrez]
PHST- 2012/07/05 06:00 [pubmed]
PHST- 2013/06/08 06:00 [medline]
AID - 10.1007/s00417-012-2096-3 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2013 Feb;251(2):591-5. doi: 
      10.1007/s00417-012-2096-3. Epub 2012 Jul 4.