PMID- 22762717
OWN - NLM
STAT- MEDLINE
DCOM- 20130104
LR  - 20151119
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 110
IP  - 8
DP  - 2012 Oct 15
TI  - Incremental value of late gadolinium enhancement for management of patients with 
      hypertrophic cardiomyopathy.
PG  - 1207-12
LID - S0002-9149(12)01535-4 [pii]
LID - 10.1016/j.amjcard.2012.05.064 [doi]
AB  - Cardiac magnetic resonance with late gadolinium enhancement (LGE) is a 
      well-established method for in vivo detection of myocardial scarring. Several 
      recent studies have investigated the prognostic value of LGE in patients with 
      hypertrophic cardiomyopathy (HC). We discuss the prevalence and patterns of 
      scarring in HC and its pathophysiologic significance, with focus on ventricular 
      arrhythmias and sudden cardiac death. The available evidence that myocardial scar 
      demonstrated by LGE is a good independent predictor of cardiac mortality in HC is 
      summed up. Recommendations of current guidelines for prevention of sudden cardiac 
      death in HC are discussed with regard to recent results, and the significance of 
      LGE as an emerging risk factor is pointed out. In conclusion, it is demonstrated 
      that LGE has incremental value in addition to clinical risk factors for risk 
      stratification and management of patients with HC.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Greulich, Simon
AU  - Greulich S
AD  - Department of Cardiology, Robert Bosch Medical Center, Stuttgart, Germany.
FAU - Schumm, Julia
AU  - Schumm J
FAU - Grun, Stefan
AU  - Grun S
FAU - Bruder, Oliver
AU  - Bruder O
FAU - Sechtem, Udo
AU  - Sechtem U
FAU - Mahrholdt, Heiko
AU  - Mahrholdt H
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120703
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Cardiomyopathy, Hypertrophic/*pathology
MH  - *Contrast Media
MH  - *Gadolinium
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Practice Guidelines as Topic
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Risk Assessment
MH  - Risk Factors
MH  - Survival Analysis
EDAT- 2012/07/06 06:00
MHDA- 2013/01/05 06:00
CRDT- 2012/07/06 06:00
PHST- 2012/03/09 00:00 [received]
PHST- 2012/05/04 00:00 [revised]
PHST- 2012/05/04 00:00 [accepted]
PHST- 2012/07/06 06:00 [entrez]
PHST- 2012/07/06 06:00 [pubmed]
PHST- 2013/01/05 06:00 [medline]
AID - S0002-9149(12)01535-4 [pii]
AID - 10.1016/j.amjcard.2012.05.064 [doi]
PST - ppublish
SO  - Am J Cardiol. 2012 Oct 15;110(8):1207-12. doi: 10.1016/j.amjcard.2012.05.064. 
      Epub 2012 Jul 3.