PMID- 22764299 OWN - NLM STAT- MEDLINE DCOM- 20120910 LR - 20211021 IS - 1476-1645 (Electronic) IS - 0002-9637 (Print) IS - 0002-9637 (Linking) VI - 87 IP - 1 DP - 2012 Jul TI - Comparisons of serum total IgE, IgG, and IgG1 levels in patients with and without echinococcosis-induced anaphylactic shock. PG - 104-8 LID - 10.4269/ajtmh.2012.11-0694 [doi] AB - We investigated serum total immunoglobulin E (IgE), IgG, and IgG1 levels in patients with and without echinococcosis-induced anaphylactic shock. This was a case-control study of 11 patients with echinococcosis-induced anaphylactic shock and 22 echinococcosis patients with cyst rupture but without anaphylactic shock. Blood was collected before surgery (T0), at the time of cyst rupture (T1), and shock (Tx), 1 h (T2), 1 day (T3), and 1 week (T4) after cyst rupture. Serum IgE, IgG, and IgG1 were determined by enzyme-linked immunosorbent assay. Serum IgE, IgG, and IgG1 levels were significantly higher in patients who developed anaphylactic shock at all time points. Increased pre-surgical IgG and IgG1 levels were identified to be a significant risk factors for developing anaphylactic shock. The results showed that a serum IgG concentration of 312.25 mug/mL could be used as a cut-off point to predict whether an echinococcosis patient would develop anaphylactic shock. FAU - Li, Yimei AU - Li Y AD - Department of Pain Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China. hanyuner1969@163.com FAU - Zheng, Hong AU - Zheng H FAU - Gu, Meilin AU - Gu M FAU - Cao, Xinghua AU - Cao X FAU - Wen, Hao AU - Wen H FAU - Liu, Zaoling AU - Liu Z FAU - Liu, Tao AU - Liu T LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Am J Trop Med Hyg JT - The American journal of tropical medicine and hygiene JID - 0370507 RN - 0 (Immunoglobulin G) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Anaphylaxis/*blood/etiology MH - Case-Control Studies MH - Echinococcosis/*blood/complications MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Humans MH - Immunoglobulin E/*blood MH - Immunoglobulin G/*blood MH - Male PMC - PMC3391032 EDAT- 2012/07/06 06:00 MHDA- 2012/09/11 06:00 PMCR- 2013/07/01 CRDT- 2012/07/06 06:00 PHST- 2012/07/06 06:00 [entrez] PHST- 2012/07/06 06:00 [pubmed] PHST- 2012/09/11 06:00 [medline] PHST- 2013/07/01 00:00 [pmc-release] AID - 87/1/104 [pii] AID - 10.4269/ajtmh.2012.11-0694 [doi] PST - ppublish SO - Am J Trop Med Hyg. 2012 Jul;87(1):104-8. doi: 10.4269/ajtmh.2012.11-0694.