PMID- 22771273
OWN - NLM
STAT- MEDLINE
DCOM- 20130225
LR  - 20120904
IS  - 1885-1398 (Electronic)
IS  - 1699-258X (Linking)
VI  - 8
IP  - 5
DP  - 2012 Sep-Oct
TI  - Frequency of complications and usefulness of the minor salivary gland biopsy.
PG  - 255-8
AB  - Findings of specific antibodies and histopathology data are essential for the 
      diagnosis of Sjogren syndrome (SS). Although the minor salivary gland biopsy 
      (MSGB) is technically simple, it needs to be performed in a medical institution 
      to avoid complications. OBJECTIVE: To determine the frequency of complications 
      and the usefulness of this technique. MATERIALS AND METHODS: Patients who 
      underwent a minor salivary gland biopsy for a possible diagnosis of SS at 
      Rivadavia Hospital between October 2007 and May 2010 where included. The patients 
      were seen a week and a month after the procedure for follow up. RESULTS: 
      Frequency of acute complications (n=186): 15 patients; 8.1%, 95% CI: 4.7-13.2 
      (Bleeding 7.5%, syncope 3.2%, hematoma 2.7%. No accidents occurred). Medium term 
      complications (n=164): 16 patients: 9.75%, 95% CI: 5.9-15.6 (pain 7.32%, 
      inflammation 3.66%, sensitivity disorders 3.05%, granuloma 1.22%,). No infections 
      or suture dehiscence occurred. Microscopic results: 154 biopsy reports were 
      received: glandular 90.9%, 95% CI: 85-95 (typical, sialadenitis, grade III and IV 
      infiltration). CONCLUSIONS: MSGB has very low frequency of medium term and acute 
      complications and it has high usefulness.
CI  - Copyright (c) 2011 Elsevier Espana, S.L. All rights reserved.
FAU - Lida Santiago, Maria
AU  - Lida Santiago M
AD  - Servicio de Reumatologia, Hospital Bernardino Rivadavia, Ciudad Autonoma de 
      Buenos Aires, Argentina. mrseisdedos@intramed.net
FAU - Seisdedos, Maria Renata
AU  - Seisdedos MR
FAU - Garcia Salinas, Rodrigo Nicolas
AU  - Garcia Salinas RN
FAU - Secco, Anastasia
AU  - Secco A
FAU - Marino Claverie, Lucila
AU  - Marino Claverie L
FAU - Techera, Lorena
AU  - Techera L
FAU - Takashima, Lorena
AU  - Takashima L
FAU - Aicardi, Pedro
AU  - Aicardi P
FAU - Sandi Rosales, Marco Antonio
AU  - Sandi Rosales MA
FAU - Knobel, Elizabeth
AU  - Knobel E
FAU - Magri, Sebastian Juan
AU  - Magri SJ
FAU - Catalan Pellet, Antonio Carlos
AU  - Catalan Pellet AC
LA  - eng
PT  - Journal Article
DEP - 20120706
PL  - Spain
TA  - Reumatol Clin
JT  - Reumatologia clinica
JID - 101293923
RN  - 0 (Autoantibodies)
RN  - 0 (Immunosuppressive Agents)
SB  - IM
MH  - Autoantibodies/blood
MH  - *Biopsy/adverse effects
MH  - Female
MH  - Hemorrhage/epidemiology/etiology
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Pain/epidemiology/etiology
MH  - Prospective Studies
MH  - Salivary Glands, Minor/*pathology
MH  - Sensitivity and Specificity
MH  - Sjogren's Syndrome/blood/complications/*diagnosis/drug therapy/etiology/pathology
MH  - Syncope/epidemiology/etiology
EDAT- 2012/07/10 06:00
MHDA- 2013/02/26 06:00
CRDT- 2012/07/10 06:00
PHST- 2011/10/05 00:00 [received]
PHST- 2012/03/18 00:00 [revised]
PHST- 2012/03/22 00:00 [accepted]
PHST- 2012/07/10 06:00 [entrez]
PHST- 2012/07/10 06:00 [pubmed]
PHST- 2013/02/26 06:00 [medline]
AID - S1699-258X(12)00088-5 [pii]
AID - 10.1016/j.reuma.2012.03.006 [doi]
PST - ppublish
SO  - Reumatol Clin. 2012 Sep-Oct;8(5):255-8. doi: 10.1016/j.reuma.2012.03.006. Epub 
      2012 Jul 6.