PMID- 22783987
OWN - NLM
STAT- MEDLINE
DCOM- 20130531
LR  - 20121128
IS  - 1525-6006 (Electronic)
IS  - 1064-1963 (Linking)
VI  - 34
IP  - 7
DP  - 2012
TI  - Concentration of natriuretic peptides in patients suffering from idiopathic 
      arterial hypertension and left ventricular diastolic dysfunction confirmed by 
      echocardiography.
PG  - 530-40
LID - 10.3109/10641963.2012.702831 [doi]
AB  - Concentration of natriuretic peptides (NPs) in arterial hypertension (AH) 
      patients is higher than that in healthy people. One of the first symptoms of left 
      ventricular hypertrophy (LVH) is left ventricular diastolic dysfunction (LVDD). 
      The aim of this study was to examine whether determination of NPs in blood can be 
      a useful indicator of LVDD detection in idiopathic AH patients. The study was 
      conducted on three groups of patients: group Ia, 19 patients (average age 57 +/- 3) 
      with eccentric hypertrophy; group Ib, 13 patients (59 +/- 4) with concentric 
      hypertrophy; group II, 33 patients (58 +/- 4) without AH or LVH. In all groups, 
      mitral inflow profile was evaluated with Doppler test to detect LVDD, blood flow 
      in upper right pulmonary vein, and concentration of atrial natriuretic peptide 
      (ANP), N-terminal ANP (N-ANP), brain natriuretic peptide (BNP), and N-terminal 
      BNP (N-BNP). In group Ia, significant correlations were observed between the 
      following pairs: ratio of maximum early to late mitral inflow and ANP; 
      deceleration time of early mitral inflow speed and ANP; atrial contraction (AR) 
      and ANP; atrial contraction (AR) and N-ANP; similarly, in group Ib, significant 
      correlations were observed between the following: relative wall thickness and 
      BNP; isovolumic relaxation time and BNP; AR and BNP; relative wall thickness and 
      N-BNP; isovolumic relaxation time and N-BNP; AR and N-BNP.
FAU - Irzmanski, Robert
AU  - Irzmanski R
AD  - Laboratory of Ergonomics and Exercise Physiology, Medical University of Lodz, 
      Lodz, Poland.
FAU - Pawlicki, Lucjan
AU  - Pawlicki L
FAU - Charlusz, Magdalena
AU  - Charlusz M
FAU - Kowalski, Jan
AU  - Kowalski J
LA  - eng
PT  - Journal Article
DEP - 20120711
PL  - England
TA  - Clin Exp Hypertens
JT  - Clinical and experimental hypertension (New York, N.Y. : 1993)
JID - 9305929
RN  - 0 (Natriuretic Peptides)
RN  - 85637-73-6 (Atrial Natriuretic Factor)
SB  - IM
MH  - Atrial Natriuretic Factor/blood
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Atria/physiopathology
MH  - Heart Ventricles/physiopathology
MH  - Humans
MH  - Hypertension/*blood/complications/physiopathology
MH  - Hypertrophy, Left Ventricular/complications/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptides/*blood
MH  - Ventricular Dysfunction, Left/*physiopathology
EDAT- 2012/07/13 06:00
MHDA- 2013/06/01 06:00
CRDT- 2012/07/13 06:00
PHST- 2012/07/13 06:00 [entrez]
PHST- 2012/07/13 06:00 [pubmed]
PHST- 2013/06/01 06:00 [medline]
AID - 10.3109/10641963.2012.702831 [doi]
PST - ppublish
SO  - Clin Exp Hypertens. 2012;34(7):530-40. doi: 10.3109/10641963.2012.702831. Epub 
      2012 Jul 11.