PMID- 22784276
OWN - NLM
STAT- MEDLINE
DCOM- 20130611
LR  - 20120829
IS  - 1530-8898 (Electronic)
IS  - 0898-929X (Linking)
VI  - 24
IP  - 10
DP  - 2012 Oct
TI  - Developmental differences in the control of action selection by social 
      information.
PG  - 2080-95
LID - 10.1162/jocn_a_00268 [doi]
AB  - Our everyday actions are often performed in the context of a social interaction. 
      We previously showed that, in adults, selecting an action on the basis of either 
      social or symbolic cues was associated with activations in the fronto-parietal 
      cognitive control network, whereas the presence and use of social versus symbolic 
      cues was in addition associated with activations in the temporal and medial 
      prefrontal cortex (MPFC) social brain network. Here we investigated developmental 
      changes in these two networks. Fourteen adults (21-30 years of age) and 14 
      adolescents (11-16 years) followed instructions to move objects in a set of 
      shelves. Interpretation of the instructions was conditional on the point of view 
      of a visible "director" or the meaning of a symbolic cue (Director Present vs. 
      Director Absent) and the number of potential referent objects in the shelves 
      (3-object vs. 1-object). 3-object trials elicited increased fronto-parietal and 
      temporal activations, with greater left lateral prefrontal cortex and parietal 
      activations in adults than adolescents. Social versus symbolic information led to 
      activations in superior dorsal MPFC, precuneus, and along the superior/middle 
      temporal sulci. Both dorsal MPFC and left temporal clusters exhibited a Director 
      x Object interaction, with greater activation when participants needed to 
      consider the directors' viewpoints. This effect differed with age in dorsal MPFC. 
      Adolescents showed greater activation whenever social information was present, 
      whereas adults showed greater activation only when the directors' viewpoints were 
      relevant to task performance. This study thus shows developmental differences in 
      domain-general and domain-specific PFC activations associated with action 
      selection in a social interaction context.
FAU - Dumontheil, Iroise
AU  - Dumontheil I
AD  - University College London Institute of Cognitive Neuroscience, 17 Queen Square, 
      London, WC1N 3AR, UK. i.dumontheil@ucl.ac.uk
FAU - Hillebrandt, Hauke
AU  - Hillebrandt H
FAU - Apperly, Ian A
AU  - Apperly IA
FAU - Blakemore, Sarah-Jayne
AU  - Blakemore SJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120820
PL  - United States
TA  - J Cogn Neurosci
JT  - Journal of cognitive neuroscience
JID - 8910747
SB  - IM
MH  - Acoustic Stimulation/*methods
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Female
MH  - Humans
MH  - *Interpersonal Relations
MH  - Male
MH  - Nerve Net/*growth & development
MH  - Photic Stimulation/*methods
MH  - Psychomotor Performance/*physiology
MH  - Reaction Time/*physiology
MH  - Young Adult
EDAT- 2012/07/13 06:00
MHDA- 2013/06/12 06:00
CRDT- 2012/07/13 06:00
PHST- 2012/07/13 06:00 [entrez]
PHST- 2012/07/13 06:00 [pubmed]
PHST- 2013/06/12 06:00 [medline]
AID - 10.1162/jocn_a_00268 [doi]
PST - ppublish
SO  - J Cogn Neurosci. 2012 Oct;24(10):2080-95. doi: 10.1162/jocn_a_00268. Epub 2012 
      Aug 20.