PMID- 22784301
OWN - NLM
STAT- MEDLINE
DCOM- 20121226
LR  - 20131121
IS  - 1557-9077 (Electronic)
IS  - 1050-7256 (Linking)
VI  - 22
IP  - 8
DP  - 2012 Aug
TI  - Hashimoto's thyroiditis presenting as acute painful thyroiditis and as a 
      manifestation of an immune reconstitution inflammatory syndrome in a human 
      immunodeficiency virus-seropositive patient.
PG  - 853-5
LID - 10.1089/thy.2012.0055 [doi]
AB  - BACKGROUND: An immune reconstitution inflammatory syndrome (IRIS) may complicate 
      immune restoration following start of antiretroviral therapy (ART) in human 
      immunodeficiency virus (HIV)-infected patients. The occurrence of Graves' disease 
      in the setting of an IRIS is well recognized. We hereby report a case of 
      Hashimoto's thyroiditis, presenting as an acute painful thyroiditis, and as a 
      complication of IRIS. SUMMARY: A painful acute thyroiditis with thyrotoxicosis 
      occurred in a 37-year-old HIV-infected woman 10 months after initiation of ART. 
      This thyroiditis was associated with the appearance of a high titer of 
      anti-thyroid peroxidase (anti-TPO) antibodies and was followed by persistent 
      hypothyroidism, requiring thyroxine replacement therapy. CONCLUSIONS: Hashimoto's 
      thyroiditis may present as an acute thyroiditis with thyrotoxicosis in 
      HIV-infected patients after initiation of ART. Clinicians caring for HIV-infected 
      patients should be aware of this possible association.
FAU - Visser, Roos
AU  - Visser R
AD  - Department of Internal Medicine, Radboud University Nijmegen Medical Center, 
      Nijmegen, The Netherlands.
FAU - de Mast, Quirijn
AU  - de Mast Q
FAU - Netea-Maier, Romana T
AU  - Netea-Maier RT
FAU - van der Ven, Andre J A M
AU  - van der Ven AJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120711
PL  - United States
TA  - Thyroid
JT  - Thyroid : official journal of the American Thyroid Association
JID - 9104317
RN  - 0 (Anti-Retroviral Agents)
RN  - EC 1.11.1.8 (Iodide Peroxidase)
RN  - Q51BO43MG4 (Thyroxine)
SB  - IM
MH  - Adult
MH  - Anti-Retroviral Agents/therapeutic use
MH  - Female
MH  - HIV Infections/complications/drug therapy
MH  - Hashimoto Disease/*complications/drug therapy
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*etiology
MH  - Iodide Peroxidase/immunology
MH  - Thyroiditis, Autoimmune/*complications
MH  - Thyrotoxicosis/*etiology
MH  - Thyroxine/therapeutic use
EDAT- 2012/07/13 06:00
MHDA- 2012/12/27 06:00
CRDT- 2012/07/13 06:00
PHST- 2012/07/13 06:00 [entrez]
PHST- 2012/07/13 06:00 [pubmed]
PHST- 2012/12/27 06:00 [medline]
AID - 10.1089/thy.2012.0055 [doi]
PST - ppublish
SO  - Thyroid. 2012 Aug;22(8):853-5. doi: 10.1089/thy.2012.0055. Epub 2012 Jul 11.