PMID- 22801289
OWN - NLM
STAT- MEDLINE
DCOM- 20150819
LR  - 20211021
IS  - 2617-2402 (Electronic)
IS  - 0333-7308 (Print)
IS  - 0333-7308 (Linking)
VI  - 49
IP  - 2
DP  - 2012
TI  - Stress and support for parents of youth with bipolar disorder.
PG  - 104-10
AB  - BACKGROUND: This article reviews stress related to parenting a youth with bipolar 
      disorder (BD), maladaptive coping, immunologic and physical functioning related 
      to chronic stress; presents preliminary findings about the association between 
      immune parameters and health conditions, mental health indices and interpersonal 
      functioning in parents of children with mood disorders; and provides 
      recommendations for stress management based on clinical trials of family-based 
      psychoeducational psychotherapy (PEP). DATA: Interleukin-6 (IL-6), tumor necrosis 
      factor-alpha (TNF-alpha), C-reactive protein (CRP), Epstein Barr Virus (EBV), 
      nutritional markers and measures of physical health, mental health and 
      interpersonal functioning were collected from 26 parents of mood disordered 
      children. Higher CRP was associated with more perceived stress, more depression, 
      increased incidence of illness/ physical conditions, and lower albumin levels. 
      Elevated IL-6 was associated with higher nicotine use. LIMITATIONS: Sample size 
      and demographics were restricted, limiting generalizability. CONCLUSION: Pilot 
      data are consistent with literature from adult caregivers, and suggest caregivers 
      who are more stressed also evidence some signs of immune abnormality. 
      Evidence-based strategies to support parents are discussed.
FAU - Nadkarni, Redha B
AU  - Nadkarni RB
AD  - Behavioral Health Services, Nationwide Children's Hospital, Columbus, Ohio, 
      U.S.A.
FAU - Fristad, Mary A
AU  - Fristad MA
LA  - eng
GR  - R01 MH061512/MH/NIMH NIH HHS/United States
GR  - R01MH061512/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Israel
TA  - Isr J Psychiatry Relat Sci
JT  - The Israel journal of psychiatry and related sciences
JID - 8108287
SB  - IM
MH  - Adult
MH  - Bipolar Disorder/*nursing
MH  - Caregivers/psychology
MH  - Child
MH  - Family Therapy/methods
MH  - Humans
MH  - Parents/*psychology
MH  - Pilot Projects
MH  - *Social Support
MH  - Stress, Psychological/etiology/*immunology/therapy
PMC - PMC4348006
MID - NIHMS608678
EDAT- 2012/07/18 06:00
MHDA- 2015/08/20 06:00
PMCR- 2015/03/03
CRDT- 2012/07/18 06:00
PHST- 2012/07/18 06:00 [entrez]
PHST- 2012/07/18 06:00 [pubmed]
PHST- 2015/08/20 06:00 [medline]
PHST- 2015/03/03 00:00 [pmc-release]
PST - ppublish
SO  - Isr J Psychiatry Relat Sci. 2012;49(2):104-10.