PMID- 22802534 OWN - NLM STAT- MEDLINE DCOM- 20131017 LR - 20220409 IS - 1940-1574 (Electronic) IS - 0003-3197 (Linking) VI - 64 IP - 6 DP - 2013 Aug TI - Neutrophil to lymphocyte ratio is associated with the severity of coronary artery disease in patients with ST-segment elevation myocardial infarction. PG - 423-9 LID - 10.1177/0003319712453305 [doi] AB - We assessed the relationship between the severity of coronary artery disease assessed by SYNTAX score (SS) and neutrophil to lymphocyte ratio (N:L ratio) in patients with ST elevation myocardial infarction (STEMI). In total, 840 patients with STEMI in whom primary percutaneous coronary intervention was performed were prospectively included (622 male, 218 female; mean age 58.6 +/- 12.4 years). Total and differential leukocyte counts and other biochemical markers were measured at admission. Patients were categorized into tertiles on the basis of SS. The N:L ratio of SShigh group was higher compared with SSlow and SSmid groups (P < .001 for all). Multivariate regression analysis showed that N:L ratio (beta = .277, P < .001), ejection fraction (beta = -.086, P = .012), age (beta = .104, P = .004), and diabetes (beta = .152, P < .001) were the independent predictors for SS in patients with STEMI. FAU - Sahin, Durmus Yildiray AU - Sahin DY AD - Department of Cardiology, Adana Numune Education and Research Hospital, Adana, Turkey. dysahin79@hotmail.com FAU - Elbasan, Zafer AU - Elbasan Z FAU - Gur, Mustafa AU - Gur M FAU - Yildiz, Ali AU - Yildiz A FAU - Akpinar, Onur AU - Akpinar O FAU - Icen, Yahya Kemal AU - Icen YK FAU - Turkoglu, Caner AU - Turkoglu C FAU - Tekin, Kamuran AU - Tekin K FAU - Kuloglu, Osman AU - Kuloglu O FAU - Cayli, Murat AU - Cayli M LA - eng PT - Journal Article DEP - 20120716 PL - United States TA - Angiology JT - Angiology JID - 0203706 SB - IM MH - Adult MH - Aged MH - Chi-Square Distribution MH - Coronary Angiography MH - Coronary Artery Disease/complications/diagnostic imaging/*immunology/therapy MH - Female MH - Humans MH - Linear Models MH - Lymphocyte Count MH - Lymphocytes/*immunology MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Myocardial Infarction/diagnostic imaging/*immunology/therapy MH - Neutrophils/*immunology MH - Percutaneous Coronary Intervention MH - Predictive Value of Tests MH - Prospective Studies MH - Risk Factors MH - Severity of Illness Index OTO - NOTNLM OT - lymphocyte OT - myocardial infarction OT - neutrophil EDAT- 2012/07/18 06:00 MHDA- 2013/10/18 06:00 CRDT- 2012/07/18 06:00 PHST- 2012/07/18 06:00 [entrez] PHST- 2012/07/18 06:00 [pubmed] PHST- 2013/10/18 06:00 [medline] AID - 0003319712453305 [pii] AID - 10.1177/0003319712453305 [doi] PST - ppublish SO - Angiology. 2013 Aug;64(6):423-9. doi: 10.1177/0003319712453305. Epub 2012 Jul 16.