PMID- 22816036 OWN - NLM STAT- MEDLINE DCOM- 20121210 LR - 20211021 IS - 1999-4915 (Electronic) IS - 1999-4915 (Linking) VI - 4 IP - 6 DP - 2012 Jun TI - Recent progress in studies of arterivirus- and coronavirus-host interactions. PG - 980-1010 LID - 10.3390/v4060980 [doi] AB - Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in critical economic damage to animal industries. This review discusses recent progress in studies of virus-host interactions during animal and human coronavirus and arterivirus infections, with emphasis on IBV-host cell interactions. These interactions may be directly involved in viral replication or lead to the alteration of certain signaling pathways, such as cell stress response and innate immunity, to facilitate viral replication and pathogenesis. FAU - Zhong, Yanxin AU - Zhong Y AD - School of Biological Sciences, Nanyang Technological Sciences, 60 Nanyang Drive, Singapore 637551, Singapore. ZH0007IN@ntu.edu.sg FAU - Tan, Yong Wah AU - Tan YW FAU - Liu, Ding Xiang AU - Liu DX LA - eng PT - Journal Article PT - Review DEP - 20120619 PL - Switzerland TA - Viruses JT - Viruses JID - 101509722 SB - IM MH - Animals MH - Apoptosis MH - Arterivirus/*physiology MH - Arterivirus Infections/*immunology/*metabolism MH - Cell Cycle MH - Coronavirus/*physiology MH - Coronavirus Infections/*immunology/*metabolism MH - *Host-Pathogen Interactions MH - Humans MH - Immunity, Innate MH - Protein Biosynthesis MH - Signal Transduction PMC - PMC3397358 OTO - NOTNLM OT - arterivirus OT - coronavirus OT - virus-host interactions EDAT- 2012/07/21 06:00 MHDA- 2012/12/12 06:00 PMCR- 2012/06/01 CRDT- 2012/07/21 06:00 PHST- 2012/05/07 00:00 [received] PHST- 2012/05/30 00:00 [revised] PHST- 2012/06/14 00:00 [accepted] PHST- 2012/07/21 06:00 [entrez] PHST- 2012/07/21 06:00 [pubmed] PHST- 2012/12/12 06:00 [medline] PHST- 2012/06/01 00:00 [pmc-release] AID - v4060980 [pii] AID - viruses-04-00980 [pii] AID - 10.3390/v4060980 [doi] PST - ppublish SO - Viruses. 2012 Jun;4(6):980-1010. doi: 10.3390/v4060980. Epub 2012 Jun 19.