PMID- 22824046 OWN - NLM STAT- MEDLINE DCOM- 20121218 LR - 20190117 IS - 1728-7731 (Electronic) IS - 1726-4901 (Linking) VI - 75 IP - 7 DP - 2012 Jul TI - Stent-assisted coil embolization of intracranial aneurysms: a single center experience. PG - 322-8 LID - 10.1016/j.jcma.2012.05.003 [doi] AB - BACKGROUND: Endovascular detachable coil embolization has become an important method in the management of intracranial aneurysms. However, coil embolization alone may fail to treat some wide-neck aneurysms. Herein, we report our experience with and outcome of stent-assisted coil embolization (SACE) of intracranial aneurysms. METHODS: Over a 5-year period, a total of 59 patients diagnosed with 63 intracranial aneurysms underwent SACE. Of the total 63 aneurysms, 6 aneurysms were treated by SACE as a salvageable procedure because of coil instability after detachment. There were 17 men and 42 women enrolled in the study, with ages ranging from 24 to 86 years (mean: 60 years). We retrospectively assessed the clinical data, aneurysm characteristics, and angiographic and clinical outcomes of all patient cases. RESULTS: The mean aneurysm size was 9.4 mm, and the mean neck size was 5.5 mm. Clinical and angiographic follow-up exceeding 6 months were available in 51 and 40 patients, respectively. The mean clinical follow-up time was 28 months (range: 6-49 months). Successful stent deployment was found in 60 aneurysms (95%). Midterm total or subtotal angiographic aneurismal occlusion was obtained in 56 aneurysms (89%), with further thrombosis of the aneurismal sac occurring in 4 (10%). Stable coiling aneurysm was found in 24 (78%), aneurysm recurrence was observed in 5 (13%), and permanent procedural morbidity was observed in two patients (3.4%). During the follow-up period, there were no hemorrhagic events and no stent displacement. CONCLUSION: Despite a modest procedural complication rate, and some evidence of aneurismal recurrence, SACE was proved to be both effective and safe in managing wide-neck intracranial aneurysms. Our results also demonstrated the midterm durability and stability of aneurysm treated by SACE. Furthermore, SACE can be a salvageable procedure in cases with coil instability after detachment. CI - Copyright (c) 2012. Published by Elsevier B.V. FAU - Luo, Chao-Bao AU - Luo CB AD - Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. cbluo@vghtpe.gov.tw FAU - Teng, Michael Mu-Huo AU - Teng MM FAU - Chang, Feng-Chi AU - Chang FC FAU - Lin, Chung-Jung AU - Lin CJ FAU - Guo, Wan-Yuo AU - Guo WY FAU - Chang, Cheng-Yen AU - Chang CY LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20120629 PL - Netherlands TA - J Chin Med Assoc JT - Journal of the Chinese Medical Association : JCMA JID - 101174817 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Embolization, Therapeutic/*methods MH - Female MH - Follow-Up Studies MH - Humans MH - Intracranial Aneurysm/*therapy MH - Male MH - Middle Aged MH - Retrospective Studies MH - *Stents EDAT- 2012/07/25 06:00 MHDA- 2012/12/19 06:00 CRDT- 2012/07/25 06:00 PHST- 2011/03/07 00:00 [received] PHST- 2011/12/29 00:00 [accepted] PHST- 2012/07/25 06:00 [entrez] PHST- 2012/07/25 06:00 [pubmed] PHST- 2012/12/19 06:00 [medline] AID - S1726-4901(12)00112-8 [pii] AID - 10.1016/j.jcma.2012.05.003 [doi] PST - ppublish SO - J Chin Med Assoc. 2012 Jul;75(7):322-8. doi: 10.1016/j.jcma.2012.05.003. Epub 2012 Jun 29.