PMID- 22825256
OWN - NLM
STAT- MEDLINE
DCOM- 20130712
LR  - 20211021
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Linking)
VI  - 29
IP  - 2
DP  - 2013 Feb
TI  - Is contrast-enhanced cardiac magnetic resonance imaging at 3 T superior to 1.5 T 
      for detection of coronary artery disease?
PG  - 355-61
LID - 10.1007/s10554-012-0099-0 [doi]
AB  - The aim is to compare a compiled clinical routine cardiac magnetic resonance 
      (CMR) imaging protocol performed at both 1.5 and 3 T in patients with suspected 
      coronary artery disease (CAD) undergoing coronary X-ray angiography. CMR 
      including adenosine perfusion and late gadolinium enhancement (LGE) at 1.5 T has 
      been established for noninvasive detection of relevant CAD. However, little is 
      known about the potential advantages of 3 T to detect CAD. Fifty-two evaluable 
      patients (62.3 +/- 10.2 years) were included into the study. All patients were 
      scanned at both 1.5 and 3 T including adenosine stress and rest perfusion, and 
      LGE imaging. CMR images were analyzed by two blinded readers in consensus. X-Ray 
      angiography served as the reference method. A significant CAD was diagnosed by 
      quantitative coronary analysis. Diagnostic accuracy of the combined analysis of 
      perfusion and LGE imaging yielded better values at 1.5 and 3 T than the analysis 
      of perfusion images alone. Specificity and sensitivity at 3 T was superior to 1.5 
      T in detecting coronary stenoses >/=50 % (90 vs. 75 % and 84.4 vs. 75 %) and >/=70 % 
      (88 vs. 80 % and 96.3 vs. 88.9 %). This study showed that CMR at 3 T in a routine 
      clinical setting is superior to 1.5 T in detection of significant CAD. 3 T might 
      become the preferred CMR field strength for evaluation of CAD in clinical 
      practice.
FAU - Walcher, Thomas
AU  - Walcher T
AD  - Department of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 
      89081, Ulm, Germany.
FAU - Ikuye, Katharina
AU  - Ikuye K
FAU - Rottbauer, Wolfgang
AU  - Rottbauer W
FAU - Wohrle, Jochen
AU  - Wohrle J
FAU - Bernhardt, Peter
AU  - Bernhardt P
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120724
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
RN  - 0 (Contrast Media)
RN  - 0 (Organometallic Compounds)
RN  - 0 (Vasodilator Agents)
RN  - 6HG8UB2MUY (Meglumine)
RN  - K72T3FS567 (Adenosine)
RN  - L0ND3981AG (gadoterate meglumine)
SB  - IM
MH  - Adenosine
MH  - Aged
MH  - Contrast Media
MH  - Coronary Angiography
MH  - Coronary Artery Disease/*diagnosis/diagnostic imaging/pathology
MH  - Coronary Stenosis/*diagnosis/diagnostic imaging/pathology
MH  - Coronary Vessels/diagnostic imaging/*pathology
MH  - Early Diagnosis
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Meglumine
MH  - Middle Aged
MH  - Organometallic Compounds
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Vasodilator Agents
EDAT- 2012/07/25 06:00
MHDA- 2013/07/16 06:00
CRDT- 2012/07/25 06:00
PHST- 2012/04/27 00:00 [received]
PHST- 2012/07/09 00:00 [accepted]
PHST- 2012/07/25 06:00 [entrez]
PHST- 2012/07/25 06:00 [pubmed]
PHST- 2013/07/16 06:00 [medline]
AID - 10.1007/s10554-012-0099-0 [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2013 Feb;29(2):355-61. doi: 10.1007/s10554-012-0099-0. 
      Epub 2012 Jul 24.