PMID- 22837996 OWN - NLM STAT- MEDLINE DCOM- 20130114 LR - 20220331 IS - 1934-3418 (Electronic) IS - 1078-4519 (Linking) VI - 41 IP - 6 DP - 2012 Jun TI - Correlation between cervical spine sagittal alignment and clinical outcome after anterior cervical discectomy and fusion. PG - E81-4 AB - Studies have shown that maintenance of lordosis improves outcomes after anterior cervical discectomy and fusion (ACDF). The relationship between maintenance or restoration of lordosis after ACDF and health-related quality of life (HRQOL) measures has not been evaluated. Preoperative and 2-year postoperative cervical lordosis (C2-C7) and segmental lordosis were measured from upright lateral cervical spine radiographs in patients who had ACDF. Data on the Neck Disability Index (NDI), Short- Form-36 Physical Composite Summary Score, arm, and neck pain scores were also collected. Paired t-tests were used to compare preoperative and 2-year postoperative radiographic measures and HRQOL measures. Receiver operating characteristic curves were constructed to identify sagittal parameters that predict achievement of a Minimum Clinically Important Difference (MCID) in outcome measures. One hundred one patients (75 female; mean age, 52 years) were included. There was improvement in all HRQOL measures from preoperative to 2 years postoperative. There was no significant difference in preoperative and 2-year postoperative sagittal alignment. Receiver operating characteristic curve analysis showed that a postoperative cervical lordosis of at least 6 degrees predicted achievement of MCID for NDI (8 point change in NDI). This suggests that maintenance or restoration of overall cervical lordosis is important in achieving a successful result after ACDF. FAU - Gum, Jeffrey L AU - Gum JL AD - Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA. FAU - Glassman, Steven D AU - Glassman SD FAU - Douglas, Lonnie R AU - Douglas LR FAU - Carreon, Leah Y AU - Carreon LY LA - eng PT - Journal Article PL - United States TA - Am J Orthop (Belle Mead NJ) JT - American journal of orthopedics (Belle Mead, N.J.) JID - 9502918 SB - IM MH - Adult MH - Aged MH - Cervical Vertebrae/diagnostic imaging/*surgery MH - *Diskectomy MH - Female MH - Humans MH - Lordosis/diagnostic imaging/*surgery MH - Male MH - Middle Aged MH - Neck Pain/diagnostic imaging/surgery MH - Radiography MH - Range of Motion, Articular/*physiology MH - *Spinal Fusion MH - Treatment Outcome EDAT- 2012/07/28 06:00 MHDA- 2013/01/15 06:00 CRDT- 2012/07/28 06:00 PHST- 2012/07/28 06:00 [entrez] PHST- 2012/07/28 06:00 [pubmed] PHST- 2013/01/15 06:00 [medline] PST - ppublish SO - Am J Orthop (Belle Mead NJ). 2012 Jun;41(6):E81-4.