PMID- 22840535
OWN - NLM
STAT- MEDLINE
DCOM- 20130103
LR  - 20161125
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 89
IP  - 8
DP  - 2012 Nov
TI  - Persistent organic pollutants (POPs) in human milk: a biomonitoring study in 
      rural areas of Flanders (Belgium).
PG  - 988-94
LID - 10.1016/j.chemosphere.2012.06.058 [doi]
AB  - To collect information on the concentrations of persistent organic pollutants 
      (POPs) in the rural areas in Flanders (Belgium), 84 breastfeeding mothers were 
      recruited in rural communities in East and West Flanders and Flemish Brabant in 
      2009-2010. Polychlorinated biphenyl (PCB) congeners, organochlorine pesticides, 
      brominated flame retardants, perfluorinated compounds, polychlorinated 
      dibenzodioxines and dibenzofurans, and dioxin-like PCBs were measured in 
      individual milk samples and in a pooled milk sample, while some additional 
      pollutants were only measured in the pooled sample. For most pollutants, the 
      concentrations in this study were lower or comparable to the concentrations 
      measured in the pooled Belgian sample of the WHO human milk study of 2006, except 
      for the pesticides dichlorodiphenyltrichloroethane DDT (+25% for SigmaDDT and 
      metabolites) and trans-nonachlor (+94%), and for the brominated flame retardant 
      hexachlorocyclododecane HBCD (+153%). Perfluorinated compounds were for the first 
      time determined in human milk samples from Belgium and the concentrations were 
      comparable to those from other European countries. Also, interesting associations 
      were found between the concentrations of POPs measured in human milk and personal 
      characteristics as well as dietary habits of the study population. PFOS en PFOA 
      concentrations were significantly higher in milk of primiparous participants 
      compared to mothers who gave birth to their second child. Lower brominated PBDE 
      congeners increased with increasing BMI of the mothers (p=0.01 for BDE 47, p=0.02 
      for BDE 99 and p=0.02 for BDE 100). Participants consuming milk or dairy products 
      daily had significant higher concentrations of SigmaDDTs (p=0.03) and oxychlordane 
      (p=0.047) in their human milk samples.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Croes, K
AU  - Croes K
AD  - Free University of Brussels, Department of Analytical and Environmental 
      Chemistry, Brussels, Belgium. kim.croes@vub.ac.be
FAU - Colles, A
AU  - Colles A
FAU - Koppen, G
AU  - Koppen G
FAU - Govarts, E
AU  - Govarts E
FAU - Bruckers, L
AU  - Bruckers L
FAU - Van de Mieroop, E
AU  - Van de Mieroop E
FAU - Nelen, V
AU  - Nelen V
FAU - Covaci, A
AU  - Covaci A
FAU - Dirtu, A C
AU  - Dirtu AC
FAU - Thomsen, C
AU  - Thomsen C
FAU - Haug, L S
AU  - Haug LS
FAU - Becher, G
AU  - Becher G
FAU - Mampaey, M
AU  - Mampaey M
FAU - Schoeters, G
AU  - Schoeters G
FAU - Van Larebeke, N
AU  - Van Larebeke N
FAU - Baeyens, W
AU  - Baeyens W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120726
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Benzofurans)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Flame Retardants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 0 (Polybrominated Biphenyls)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Polymers)
RN  - 0 (polychlorodibenzofuran)
RN  - CIW5S16655 (DDT)
SB  - IM
MH  - Belgium
MH  - Benzofurans/analysis
MH  - DDT/analysis/metabolism
MH  - *Environmental Monitoring
MH  - Environmental Pollutants/*analysis
MH  - Female
MH  - Flame Retardants/analysis
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*analysis
MH  - Milk, Human/*chemistry
MH  - Pesticides/analysis
MH  - Polybrominated Biphenyls/analysis/metabolism
MH  - Polychlorinated Dibenzodioxins/analogs & derivatives/analysis
MH  - Polymers/analysis
MH  - Rural Population
EDAT- 2012/07/31 06:00
MHDA- 2013/01/04 06:00
CRDT- 2012/07/31 06:00
PHST- 2012/02/28 00:00 [received]
PHST- 2012/06/06 00:00 [revised]
PHST- 2012/06/30 00:00 [accepted]
PHST- 2012/07/31 06:00 [entrez]
PHST- 2012/07/31 06:00 [pubmed]
PHST- 2013/01/04 06:00 [medline]
AID - S0045-6535(12)00867-3 [pii]
AID - 10.1016/j.chemosphere.2012.06.058 [doi]
PST - ppublish
SO  - Chemosphere. 2012 Nov;89(8):988-94. doi: 10.1016/j.chemosphere.2012.06.058. Epub 
      2012 Jul 26.