PMID- 22840540
OWN - NLM
STAT- MEDLINE
DCOM- 20130103
LR  - 20220309
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 89
IP  - 8
DP  - 2012 Nov
TI  - Serum concentrations of persistent organic pollutants (POPs) in the inhabitants 
      of a Sicilian city.
PG  - 970-4
LID - 10.1016/j.chemosphere.2012.06.054 [doi]
AB  - BACKGROUND: Polychlorinated biphenyls (PCBs) and organochlorine pesticides are 
      common environmental contaminants that have been associated with human health 
      problems. OBJECTIVES: To assess serum concentrations of several organochlorine 
      contaminants in general population living in a city with an ancient agricultural 
      tradition and to identify possible exposure sources in Sicily. METHODS: A 
      cross-sectional study was conducted on 101 individuals. Each participant answered 
      a face-to-face questionnaire submitted by well-trained personnel and provided a 
      serum sample which was analyzed for the concentrations of PCBs, HCB, HCHs and 
      DDTs by using gas-chromatography coupled with mass spectrometry. RESULTS: HCB, 
      p,p'-DDE, PCB 138, PCB 153 and PCB 180 were detected in more than 80% of the 
      study participants. The ng g(-1) lipid median concentrations were: 18.6 for HCB; 
      175.1 for p,p'-DDE; 22. for PCB 138; 32.5 for PCB 153 and 23.0 for PCB 180. PCB 
      153 and PCB 138, PCB 138 and PCB 180, PCB 153 and PCB 180, and p,p'-DDE and HCB 
      showed a high correlation each other (p<0.05). HCB and p,p'-DDE concentrations 
      were significantly higher in subjects >49 years old (adj-p=0.03 in 50-69 years 
      old and adj-p<0.001 in >69 years old, respectively) whereas PCB 138, PCB 153 and 
      PCB 180 concentrations were higher in males (adj-p=0.03), in subjects >69 years 
      old (adj-p=0.04) and in current smokers (adj-p=0.04). CONCLUSIONS: The present 
      study shows that serum concentrations of organochlorine compounds detected in 
      subjects living in a small Sicilian city with ancient agricultural tradition are 
      similar to those found in subjects living in urban areas of other countries. 
      However, further investigations are needed to compare data from rural/urban areas 
      in the same country, assessing correlations between serum concentrations of 
      several chemical compounds and potential health effects in general population.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Amodio, Emanuele
AU  - Amodio E
AD  - Department of Sciences for Health Promotion G. D'Alessandro, University of 
      Palermo, Italy. emanuele.amodio@unipa.it
FAU - Turci, Roberta
AU  - Turci R
FAU - Massenti, Maria Fatima
AU  - Massenti MF
FAU - Di Gaudio, Francesca
AU  - Di Gaudio F
FAU - Minoia, Claudio
AU  - Minoia C
FAU - Vitale, Francesco
AU  - Vitale F
FAU - Firenze, Alberto
AU  - Firenze A
FAU - Calamusa, Giuseppe
AU  - Calamusa G
LA  - eng
PT  - Journal Article
DEP - 20120726
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticide Residues)
RN  - 4Z87H0LKUY (Hexachlorobenzene)
RN  - CIW5S16655 (DDT)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cities
MH  - Cross-Sectional Studies
MH  - DDT/blood
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Gas Chromatography-Mass Spectrometry
MH  - Hexachlorobenzene/blood
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*blood
MH  - Male
MH  - Middle Aged
MH  - Pesticide Residues/blood
MH  - Polychlorinated Biphenyls/*blood
MH  - Sicily
MH  - Surveys and Questionnaires
EDAT- 2012/07/31 06:00
MHDA- 2013/01/04 06:00
CRDT- 2012/07/31 06:00
PHST- 2011/12/04 00:00 [received]
PHST- 2012/05/10 00:00 [revised]
PHST- 2012/06/30 00:00 [accepted]
PHST- 2012/07/31 06:00 [entrez]
PHST- 2012/07/31 06:00 [pubmed]
PHST- 2013/01/04 06:00 [medline]
AID - S0045-6535(12)00863-6 [pii]
AID - 10.1016/j.chemosphere.2012.06.054 [doi]
PST - ppublish
SO  - Chemosphere. 2012 Nov;89(8):970-4. doi: 10.1016/j.chemosphere.2012.06.054. Epub 
      2012 Jul 26.