PMID- 22844211 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130117 LR - 20240318 IS - 1394-195X (Print) IS - 2180-4303 (Electronic) IS - 1394-195X (Linking) VI - 7 IP - 1 DP - 2000 Jan TI - Helicobacter pylori related functional dyspepsia in a defined malaysian population. PG - 22-6 AB - The objective of the study was to determine the prevalence of H. pylori in functional dyspepsia among the three main races in Malaysia. Gastric antral biopsies from 233 (98 males, 135 females; age range: 17-75 years, mean age 39.5 years) patients attending the Universiti Kebangsaan Malaysia (UKM) gastroenterology clinic were assessed for the presence of H. pylori by culture and histology. About a third of the cases (79 of 233 (34%); 34 males, 45 females; mean age 42.6 yrs) were positive for H. pylori. The presence of H. pylori was always associated with antral gastritis. Malay patients were least likely to be positive for H. pylori (10 of 88 (11.4%); 5 males, 5 females; mean age 35.7 yrs) compared to the Chinese (43 of 95 (45%); 19 males; 24 females; mean age 40.2 yrs) and Indian patients (23 of 41 (56%); 10 males, 13 females; mean age 48.1 yrs). We found that H. pylori were most common among Chinese followed by Indians. However, the relative risk for the Indians was 8.58 and 6.29 for the Chinese compared to Malays. We conclude that the prevalence of H. pylori in patients with functional dyspepsia differs considerably with respect to ethnic groups. FAU - Nafeeza, M I AU - Nafeeza MI AD - Departments of Pharmacology. FAU - Isa, M R AU - Isa MR FAU - Kudva, M V AU - Kudva MV FAU - Ishak, M S AU - Ishak MS FAU - Mazlam, M Z AU - Mazlam MZ FAU - Haron, A AU - Haron A FAU - Najib, R AU - Najib R FAU - Shahimi, M M AU - Shahimi MM LA - eng PT - Journal Article PL - Malaysia TA - Malays J Med Sci JT - The Malaysian journal of medical sciences : MJMS JID - 101126308 PMC - PMC3406213 OTO - NOTNLM OT - Helicobacter Pylori OT - Malaysia OT - dyspepsia EDAT- 2000/01/01 00:00 MHDA- 2000/01/01 00:01 PMCR- 2000/01/01 CRDT- 2012/07/31 06:00 PHST- 2012/07/31 06:00 [entrez] PHST- 2000/01/01 00:00 [pubmed] PHST- 2000/01/01 00:01 [medline] PHST- 2000/01/01 00:00 [pmc-release] AID - mjms-7-1-022 [pii] PST - ppublish SO - Malays J Med Sci. 2000 Jan;7(1):22-6.