PMID- 22850087
OWN - NLM
STAT- MEDLINE
DCOM- 20140303
LR  - 20191210
IS  - 1473-5695 (Electronic)
IS  - 0969-9546 (Linking)
VI  - 20
IP  - 4
DP  - 2013 Aug
TI  - Five-year trends in self-reported recreational drugs associated with presentation 
      to a UK emergency department with suspected drug-related toxicity.
PG  - 263-7
LID - 10.1097/MEJ.0b013e3283573115 [doi]
AB  - OBJECTIVE: User surveys show that there have been significant changes over the 
      last decade in the recreational drugs that are available and being used. This 
      study aims to determine whether there have been similar trends in the drug(s) 
      used by individuals presenting to the emergency department (ED) with acute 
      recreational drug toxicity. METHODS: Data on all poisoned patients presenting to 
      our large inner-city ED are recorded prospectively on a dedicated clinical 
      toxicology database. Presentations relating to the use of classical recreational 
      drugs and/or novel psychoactive substances were identified retrospectively 
      between 1 January 2006 and 31 December 2010. RESULTS: There was a significant 
      increase between 2006 and 2010 in the number of individuals reporting the use of 
      cocaine (119-222), gamma-hydroxybutyrate/gamma-butyrolactone (158-270), ketamine (58-81) 
      and cannabis (18-68) and novel psychoactive substances (seven to 98). In 
      particular, there was an increase in cathinones reported from none in 2006 to 82 
      in 2010. Only 3,4-methylenedioxymethamphetamine (MDMA) was associated with a 
      downward trend in reported use from 140 in 2006 to 103 in 2010. CONCLUSION: Data 
      collection on the drug(s) used in individuals presenting to specialist clinical 
      toxicology centres and/or sentinel EDs across Europe with acute recreational drug 
      toxicity would help to determine the true pattern(s) of drug use and the acute 
      harm associated with this use across Europe and trends over time.
FAU - Wood, David M
AU  - Wood DM
AD  - Department of Clinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and 
      King's Health Partners, London, UK. David.Wood@gstt.nhs.uk
FAU - Greene, Shaun L
AU  - Greene SL
FAU - Dargan, Paul I
AU  - Dargan PI
LA  - eng
PT  - Journal Article
PL  - England
TA  - Eur J Emerg Med
JT  - European journal of emergency medicine : official journal of the European Society 
      for Emergency Medicine
JID - 9442482
RN  - 0 (Illicit Drugs)
RN  - 690G0D6V8H (Ketamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Amphetamine-Related Disorders/epidemiology
MH  - Cocaine-Related Disorders/epidemiology
MH  - Drug-Related Side Effects and Adverse Reactions/*epidemiology
MH  - Emergency Service, Hospital/*trends
MH  - Humans
MH  - Illicit Drugs/*toxicity
MH  - Ketamine/toxicity
MH  - London/epidemiology
MH  - Marijuana Abuse/epidemiology
MH  - N-Methyl-3,4-methylenedioxyamphetamine/toxicity
MH  - Retrospective Studies
EDAT- 2012/08/02 06:00
MHDA- 2014/03/04 06:00
CRDT- 2012/08/02 06:00
PHST- 2012/08/02 06:00 [entrez]
PHST- 2012/08/02 06:00 [pubmed]
PHST- 2014/03/04 06:00 [medline]
AID - 10.1097/MEJ.0b013e3283573115 [doi]
PST - ppublish
SO  - Eur J Emerg Med. 2013 Aug;20(4):263-7. doi: 10.1097/MEJ.0b013e3283573115.