PMID- 22867837
OWN - NLM
STAT- MEDLINE
DCOM- 20130129
LR  - 20161125
IS  - 1532-8171 (Electronic)
IS  - 0735-6757 (Linking)
VI  - 30
IP  - 8
DP  - 2012 Oct
TI  - Unnecessary surgery for acute abdomen secondary to angiotensin-converting enzyme 
      inhibitor use.
PG  - 1607-12
LID - S0735-6757(11)00536-5 [pii]
LID - 10.1016/j.ajem.2011.10.028 [doi]
AB  - Acute abdominal pain is the reason for 5% to 10% of all emergency department 
      visits. In 1 in every 9 patients, operated on for an acute abdomen, laparotomy is 
      negative. In a minority of patients, the acute abdomen is caused by side effects 
      of medication. We present a case of unnecessary abdominal surgery in a patient 
      with acute abdominal pain caused by intestinal angioedema (AE), which was 
      eventually due to angiotensin-converting enzyme inhibitor (ACE-i) use. We hope 
      that this case report increases awareness of this underdiagnosed side effect. 
      Emergency department physicians, surgeons, internists, and family physicians 
      should always consider ACE-i in the differential diagnosis of unexplained 
      abdominal pain. Since early withdrawal of the medication causing intestinal AE 
      can prevent further complications and, in some cases, needless surgery, we 
      propose an altered version of the known diagnostic algorithm, in which ACE-i and 
      nonsteroidal anti-inflammatory drugs-induced AE is excluded at an early stage.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - de Graaff, Laura C G
AU  - de Graaff LC
AD  - Department of Internal Medicine, Reinier de Graaf Group of Hospitals, 2600GA 
      Delft, The Netherlands. degraaff@erasmusmc.nl
FAU - van Essen, Martijn
AU  - van Essen M
FAU - Schipper, Eleonora M
AU  - Schipper EM
FAU - Boom, Henk
AU  - Boom H
FAU - Duschek, Erik J J
AU  - Duschek EJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120804
PL  - United States
TA  - Am J Emerg Med
JT  - The American journal of emergency medicine
JID - 8309942
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
RN  - E7199S1YWR (Lisinopril)
SB  - IM
MH  - Abdomen, Acute/chemically induced/diagnostic imaging/*surgery
MH  - Angioedema/chemically induced/diagnosis/diagnostic imaging
MH  - Angiotensin-Converting Enzyme Inhibitors/*adverse effects
MH  - Female
MH  - Humans
MH  - Intestinal Diseases/chemically induced/diagnosis/diagnostic imaging
MH  - Lisinopril/adverse effects
MH  - Middle Aged
MH  - Tomography, X-Ray Computed
MH  - *Unnecessary Procedures
EDAT- 2012/08/08 06:00
MHDA- 2013/01/30 06:00
CRDT- 2012/08/08 06:00
PHST- 2011/10/28 00:00 [received]
PHST- 2011/10/29 00:00 [accepted]
PHST- 2012/08/08 06:00 [entrez]
PHST- 2012/08/08 06:00 [pubmed]
PHST- 2013/01/30 06:00 [medline]
AID - S0735-6757(11)00536-5 [pii]
AID - 10.1016/j.ajem.2011.10.028 [doi]
PST - ppublish
SO  - Am J Emerg Med. 2012 Oct;30(8):1607-12. doi: 10.1016/j.ajem.2011.10.028. Epub 
      2012 Aug 4.