PMID- 22869073 OWN - NLM STAT- MEDLINE DCOM- 20130108 LR - 20221207 IS - 1676-5680 (Electronic) IS - 1676-5680 (Linking) VI - 11 IP - 3 DP - 2012 Aug 16 TI - Nine polymorphic STR loci in the HLA region in the Shaanxi Han population of China. PG - 2534-8 LID - 10.4238/2012.July.10.8 [doi] AB - A large number of microsatellite genetic markers have been identified in the human leukocyte antigen (HLA) region. We investigated genetic polymorphism of the nine short tandem repeat (STR) loci (D6S276, MOGCA, D6S265, MIB, D6S273, G51152, TAP1CA, RING3CA, and D6S291) in the HLA region in the Shaanxi Han population. Using a fluorescence-labeled multiplex-PCR STR typing method, 6-13 alleles were detected in these nine STR loci in 150 unrelated Han Chinese from the region of Shaanxi, China. The distributions of the genotypes at these nine loci were in Hardy-Weinberg equilibrium. We conclude that these nine STR loci have a high level of genetic polymorphism; they would be useful for population genetic studies, pre-transplantation HLA typing, forensic and paternity testing, etc. FAU - Zhang, H B AU - Zhang HB AD - Key Laboratory of the National Ministry of Health for Forensic Sciences, School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, P.R. China. FAU - Wei, S G AU - Wei SG FAU - Yu, B AU - Yu B FAU - Li, L AU - Li L FAU - Lai, J H AU - Lai JH LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20120816 PL - Brazil TA - Genet Mol Res JT - Genetics and molecular research : GMR JID - 101169387 RN - 0 (Genetic Markers) RN - 0 (HLA Antigens) SB - IM MH - Asian People/*genetics MH - China MH - Chromosomes, Human, Pair 6/genetics MH - Ethnicity/genetics MH - Gene Frequency/genetics MH - Genetic Loci/*genetics MH - Genetic Markers MH - HLA Antigens/*genetics MH - Humans MH - Microsatellite Repeats/*genetics MH - *Polymorphism, Genetic EDAT- 2012/08/08 06:00 MHDA- 2013/01/09 06:00 CRDT- 2012/08/08 06:00 PHST- 2012/08/08 06:00 [entrez] PHST- 2012/08/08 06:00 [pubmed] PHST- 2013/01/09 06:00 [medline] AID - gmr1776 [pii] AID - 10.4238/2012.July.10.8 [doi] PST - epublish SO - Genet Mol Res. 2012 Aug 16;11(3):2534-8. doi: 10.4238/2012.July.10.8.