PMID- 22869382
OWN - NLM
STAT- MEDLINE
DCOM- 20131017
LR  - 20130129
IS  - 1938-2375 (Electronic)
IS  - 1542-8877 (Linking)
VI  - 43
IP  - 6 Suppl
DP  - 2012 Nov-Dec
TI  - Morphometric analysis of epiretinal membranes using SD-OCT.
PG  - S7-15
LID - 10.3928/15428877-20120726-02 [doi]
AB  - BACKGROUND AND OBJECTIVE: To determine whether the volumes of macular layers 
      before and after epiretinal membrane (ERM) peeling as measured by spectral-domain 
      optical coherence tomography (SD-OCT) correlated with best-corrected visual 
      acuity (BCVA) or ERM location. PATIENTS AND METHODS: Thirty-six eyes with 
      idiopathic ERM and 12 control eyes were imaged preoperatively and postoperatively 
      using SD-OCT. The inner, middle, and outer retinal layers were measured in the 
      temporal and nasal half of the central 1,500 mum of the macula for each of the 
      SD-OCT five raster scans and used to estimate the volumes for each group. 
      RESULTS: The inner layer volumes were larger in cases compared with control eyes. 
      The nasal inner and temporal inner layer volumes decreased after ERM removal in 
      the nasal dominant, macular dominant, and temporal dominant groups. The inner 
      layer volume decreased more temporally than nasally in the macular dominant and 
      temporal dominant groups but not in the nasal dominant group. The volume 
      decreased more in the temporal middle than the nasal middle layer for the 
      temporal dominant group. The BCVA improvement correlated with nasal inner layer 
      volume decrease and nasal outer and temporal outer layer volume increase. 
      CONCLUSION: The volume of the inner perifoveal retinal sections decreases after 
      ERM peeling, possibly representing resolution of edema or reorganization of the 
      nerve fiber layer on release of mechanical traction. Visual improvement 
      correlated with volume increase of the outer retinal layers and may represent 
      photoreceptor cell recovery after ERM peeling.
CI  - Copyright 2012, SLACK Incorporated.
FAU - Gao, Yuduan
AU  - Gao Y
AD  - Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami 
      Miller School of Medicine, Miami, Florida 33136, USA.
FAU - Smiddy, William E
AU  - Smiddy WE
LA  - eng
PT  - Journal Article
DEP - 20120802
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging
JT  - Ophthalmic surgery, lasers & imaging : the official journal of the International 
      Society for Imaging in the Eye
JID - 101155780
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Cohort Studies
MH  - Epiretinal Membrane/*pathology/physiopathology/surgery
MH  - Female
MH  - Humans
MH  - Macula Lutea/pathology
MH  - Male
MH  - Middle Aged
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity/physiology
EDAT- 2012/08/08 06:00
MHDA- 2013/10/18 06:00
CRDT- 2012/08/08 06:00
PHST- 2011/12/10 00:00 [received]
PHST- 2012/06/07 00:00 [accepted]
PHST- 2012/08/08 06:00 [entrez]
PHST- 2012/08/08 06:00 [pubmed]
PHST- 2013/10/18 06:00 [medline]
AID - 10.3928/15428877-20120726-02 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging. 2012 Nov-Dec;43(6 Suppl):S7-15. doi: 
      10.3928/15428877-20120726-02. Epub 2012 Aug 2.