PMID- 22878538
OWN - NLM
STAT- MEDLINE
DCOM- 20130715
LR  - 20190606
IS  - 1347-7439 (Electronic)
IS  - 0916-7250 (Linking)
VI  - 75
IP  - 1
DP  - 2013 Jan 31
TI  - Existence of Galphai2-expressing axon terminals in the goat main olfactory bulb.
PG  - 85-8
AB  - In rodents, Galpha(i2)-expressing sensory neurons (SNs) that co-express vomeronasal 
      receptor type 1 (V1R) are specifically found in the vomeronasal organ (VNO) and 
      project their axons to the accessory olfactory bulb (AOB). In goats, however, 
      Galpha(i2)/V1R-expressing SNs exist in both the VNO and the olfactory epithelium. 
      Thus, we examined whether the Galpha(i2)-expressing axons functionally project to the 
      main olfactory bulb (MOB). We analyzed the expression of Galpha(i2) in the olfactory 
      bulb and found small Galpha(i2)-immunoreactive clusters in the MOB. The 
      Galpha(i2)-immunoreactive axons in these clusters made synaptic contacts with 
      second-order neurons in the MOB. These results suggest that some 
      Galpha(i2)-expressing SNs functionally project their axons to the MOB in goats.
FAU - Ohara, Hiromi
AU  - Ohara H
AD  - Department of Dementia and Higher Brain Function, Integrated Neuroscience 
      Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 
      Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
FAU - Okamura, Hiroaki
AU  - Okamura H
FAU - Ichikawa, Masumi
AU  - Ichikawa M
FAU - Mori, Yuji
AU  - Mori Y
FAU - Hagino-Yamagishi, Kimiko
AU  - Hagino-Yamagishi K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120810
PL  - Japan
TA  - J Vet Med Sci
JT  - The Journal of veterinary medical science
JID - 9105360
RN  - EC 3.6.5.1 (GTP-Binding Protein alpha Subunit, Gi2)
SB  - IM
MH  - Afferent Pathways
MH  - Animals
MH  - Blotting, Western/veterinary
MH  - GTP-Binding Protein alpha Subunit, Gi2/*metabolism
MH  - Goats/*metabolism
MH  - Microscopy, Electron/veterinary
MH  - Microscopy, Fluorescence/veterinary
MH  - Olfactory Bulb/cytology/*metabolism
MH  - Presynaptic Terminals/*metabolism/ultrastructure
MH  - Sensory Receptor Cells/*metabolism
MH  - Vomeronasal Organ/*cytology
EDAT- 2012/08/11 06:00
MHDA- 2013/07/17 06:00
CRDT- 2012/08/11 06:00
PHST- 2012/08/11 06:00 [entrez]
PHST- 2012/08/11 06:00 [pubmed]
PHST- 2013/07/17 06:00 [medline]
AID - DN/JST.JSTAGE/jvms/12-0245 [pii]
AID - 10.1292/jvms.12-0245 [doi]
PST - ppublish
SO  - J Vet Med Sci. 2013 Jan 31;75(1):85-8. doi: 10.1292/jvms.12-0245. Epub 2012 Aug 
      10.