PMID- 22879462
OWN - NLM
STAT- MEDLINE
DCOM- 20130102
LR  - 20220331
IS  - 1462-0332 (Electronic)
IS  - 1462-0324 (Linking)
VI  - 51
IP  - 11
DP  - 2012 Nov
TI  - Rheumatoid arthritis and falls: the influence of disease activity.
PG  - 2051-7
LID - 10.1093/rheumatology/kes198 [doi]
AB  - OBJECTIVE: To examine the correlation between disease activity of RA and the risk 
      of falling. METHODS: Seventy-eight patients were tested. Disease activity was 
      measured with acute-phase reactants, autoantibodies, swollen and tender joint 
      count (SJC28, TJC28), pain on a visual analogue scale (VAS pain), patient and 
      evaluator global assessment of disease activity (PGA, EGA), HAQ disability index 
      (HAQ-DI), 28-joint DAS (DAS-28) and the clinical and simple disease activity 
      indexes (CDAI, SDAI). The risk of falling was evaluated by a fall assessment 
      consisting of Tinetti test (TIT), timed get up and go test (TUG), chair-rising 
      test (CRT), tandem walk and tandem stand test. RESULTS: During the last 12 
      months, 26.9% of the participants reported a fall and 46.2% mentioned the fear of 
      falling. The most evident link [Spearman's correlation (r(s))] with the results 
      of the fall assessment was found in HAQ-DI (CRT: r(s) = 0.523, TUG: r(s) = 0.620, 
      TIT: r(s) = -0.676), CDAI (CRT: r(s) = 0.460, TUG: r(s) = 0.504, TIT: 
      r(s) = -0.472), VAS pain (CRT: r(s) = 0.441, TUG: r(s) = 0.616, TIT: 
      r(s) = -0.548) PGA (CRT: r(s) = 0.473, TUG: r(s) = 0.577, TIT: r(s) = -0.520) and 
      TJC (CRT: r(s) = 0.488, TUG: r(s) = 0.394, TIT: r(s) = -0.385). Patients with 
      higher disease activity achieved poorer results in the fall assessment. 
      CONCLUSION: The strongest correlation with falls was evident for patient-reported 
      outcomes. Pain seems to be the common ground of these parameters. At the same 
      time, disease activity influences pain. The results suggest an increased 
      attention towards the risk of falling with patients of higher levels of disease 
      activity or pain, and physio- or ergotherapeutical interventions as needed.
FAU - Bohler, Christoph
AU  - Bohler C
AD  - Department of Acute Geriatric Medicine, SMZ Sophienspital, Apollogasse 19, Vienna 
      1070, Austria.
FAU - Radner, Helga
AU  - Radner H
FAU - Ernst, Michaela
AU  - Ernst M
FAU - Binder, Alexa
AU  - Binder A
FAU - Stamm, Tanja
AU  - Stamm T
FAU - Aletaha, Daniel
AU  - Aletaha D
FAU - Smolen, Josef S
AU  - Smolen JS
FAU - Koller, Marcus
AU  - Koller M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20120809
PL  - England
TA  - Rheumatology (Oxford)
JT  - Rheumatology (Oxford, England)
JID - 100883501
SB  - IM
MH  - Accidental Falls/*statistics & numerical data
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthritis, Rheumatoid/*complications/psychology
MH  - Disability Evaluation
MH  - Fear
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Musculoskeletal Pain/etiology
MH  - Pain Measurement
MH  - Prognosis
MH  - Regression Analysis
MH  - Risk Factors
MH  - Young Adult
EDAT- 2012/08/11 06:00
MHDA- 2013/01/03 06:00
CRDT- 2012/08/11 06:00
PHST- 2012/08/11 06:00 [entrez]
PHST- 2012/08/11 06:00 [pubmed]
PHST- 2013/01/03 06:00 [medline]
AID - kes198 [pii]
AID - 10.1093/rheumatology/kes198 [doi]
PST - ppublish
SO  - Rheumatology (Oxford). 2012 Nov;51(11):2051-7. doi: 10.1093/rheumatology/kes198. 
      Epub 2012 Aug 9.