PMID- 22881188
OWN - NLM
STAT- MEDLINE
DCOM- 20130118
LR  - 20131121
IS  - 1526-4602 (Electronic)
IS  - 1525-7797 (Linking)
VI  - 13
IP  - 9
DP  - 2012 Sep 10
TI  - Significantly reinforced composite fibers electrospun from silk fibroin/carbon 
      nanotube aqueous solutions.
PG  - 2859-67
LID - 10.1021/bm300877d [doi]
AB  - Microcomposite fibers of regenerated silk fibroin (RSF) and multiwalled carbon 
      nanotubes (MWNTs) were successfully prepared by an electrospinning process from 
      aqueous solutions. A quiescent blended solution and a three-dimensional Raman 
      image of the composite fibers showed that functionalized MWNTs (F-MWNTs) were 
      well dispersed in the solutions and the RSF fibers, respectively. Raman spectra 
      and wide-angle X-ray diffraction (WAXD) patterns of RSF/F-MWNT electrospun fibers 
      indicated that the composite fibers had higher beta-sheet content and crystallinity 
      than the pure RSF electrospun fibers, respectively. The mechanical properties of 
      the RSF electrospun fibers were improved drastically by incorporating F-MWNTs. 
      Compared with the pure RSF electrospun fibers, the composite fibers with 1.0 wt % 
      F-MWNTs exhibited a 2.8-fold increase in breaking strength, a 4.4-fold increase 
      in Young's modulus, and a 2.1-fold increase in breaking energy. Cytotoxicity test 
      preliminarily demonstrated that the electrospun fiber mats have good 
      biocompatibility for tissue engineering scaffolds.
FAU - Pan, Hui
AU  - Pan H
AD  - State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, 
      College of Materials Science and Engineering, Donghua University, Shanghai 
      201620, PR China.
FAU - Zhang, Yaopeng
AU  - Zhang Y
FAU - Hang, Yichun
AU  - Hang Y
FAU - Shao, Huili
AU  - Shao H
FAU - Hu, Xuechao
AU  - Hu X
FAU - Xu, Yuemin
AU  - Xu Y
FAU - Feng, Chao
AU  - Feng C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120822
PL  - United States
TA  - Biomacromolecules
JT  - Biomacromolecules
JID - 100892849
RN  - 0 (Biocompatible Materials)
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Solutions)
RN  - 059QF0KO0R (Water)
RN  - 9007-76-5 (Fibroins)
SB  - IM
MH  - Animals
MH  - Biocompatible Materials/*chemical synthesis/pharmacology
MH  - Bombyx/*chemistry
MH  - Cell Line
MH  - Cell Survival/drug effects
MH  - Dogs
MH  - Elastic Modulus
MH  - Electrochemical Techniques
MH  - Epithelial Cells/cytology/drug effects
MH  - Fibroblasts/cytology/drug effects
MH  - Fibroins/*chemistry
MH  - Mice
MH  - Molecular Structure
MH  - Nanotubes, Carbon/*chemistry
MH  - Solutions
MH  - Spectrum Analysis, Raman
MH  - Tensile Strength
MH  - Tissue Engineering
MH  - Tissue Scaffolds
MH  - Water
MH  - X-Ray Diffraction
EDAT- 2012/08/14 06:00
MHDA- 2013/01/19 06:00
CRDT- 2012/08/14 06:00
PHST- 2012/08/14 06:00 [entrez]
PHST- 2012/08/14 06:00 [pubmed]
PHST- 2013/01/19 06:00 [medline]
AID - 10.1021/bm300877d [doi]
PST - ppublish
SO  - Biomacromolecules. 2012 Sep 10;13(9):2859-67. doi: 10.1021/bm300877d. Epub 2012 
      Aug 22.