PMID- 22882478
OWN - NLM
STAT- MEDLINE
DCOM- 20121217
LR  - 20120919
IS  - 1540-8167 (Electronic)
IS  - 1045-3873 (Linking)
VI  - 23
IP  - 9
DP  - 2012 Sep
TI  - Comparison of the location of slow conduction velocity in cavotricuspid-dependent 
      atrial flutter in patients with and without prior atriotomy: different 
      arrhythmogenic basis and clinical implications for placement of atriotomy.
PG  - 988-95
LID - 10.1111/j.1540-8167.2012.02348.x [doi]
AB  - Slow Zone in CTI-Dependent Flutter After Atriotomy. INTRODUCTION: Earlier studies 
      have shown that the slow conduction zone in patients with cavotriscuspid 
      (CTI)-dependent atrial flutter without prior surgery (NS-AFL) is the CTI. 
      However, the location of this slow zone in patients with CTI-dependent flutter 
      and a prior atriotomy has not been formally studied. Identification of the slow 
      zone in patients with prior atriotomy and CTI-dependent atrial flutter (PA-AFL) 
      and comparison with NS-AFL may have important clinical implications. METHODS AND 
      RESULTS: Seventeen consecutive patients with PA-AFL and 17 consecutive patients 
      with NS-AFL were included. Conduction velocity (CV) was measured using 
      3-dimensional mapping in 3 areas around the TVA. These regions were defined as 
      the CTI area from lateral inferior vena cava orifice to coronary sinus ostium 
      (region I), mid- to upper-septum (S), and free wall (F). In region F, the CV was 
      much slower in PA-AFL than in NS-AFL patients (0.43 +/- 0.13 vs 0.76 +/- 0.26 m/s, P 
      < 0.01). However, region I was slower in NS-AFL than PA-AFL (0.57 +/- 0.18 m/s vs 
      0.84 +/- 0.24 m/s, P < 0.01). In all PA-AFL patients, the slow zone was in region 
      F. But in most (11/17) NS-AFL patients the slow zone was in region I. There was 
      no significant difference in CV in region S between the 2 groups. CONCLUSIONS: 
      Unlike NS-AFL, CTI in PA-AFL displays relatively normal conduction but the slow 
      zone is on the free wall. This arrhythmogenecity of atriotomy may perhaps be 
      avoided if the incisional line were altered to extend to the TV. (J Cardiovasc 
      Electrophysiol, Vol. 23, pp. 988-995, September 2012).
CI  - (c) 2012 Wiley Periodicals, Inc.
FAU - Yang, Bing
AU  - Yang B
AD  - Division of Cardiology, the First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Ju, Weizhu
AU  - Ju W
FAU - Chen, Hongwu
AU  - Chen H
FAU - Zhang, Fengxiang
AU  - Zhang F
FAU - Chen, Kai
AU  - Chen K
FAU - Gu, Kai
AU  - Gu K
FAU - Cao, Kejiang
AU  - Cao K
FAU - Chen, Minglong
AU  - Chen M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120807
PL  - United States
TA  - J Cardiovasc Electrophysiol
JT  - Journal of cardiovascular electrophysiology
JID - 9010756
SB  - IM
MH  - Adult
MH  - Aged
MH  - Arrhythmias, Cardiac/*etiology
MH  - Atrial Flutter/*physiopathology/surgery
MH  - Catheter Ablation
MH  - Female
MH  - Heart Atria/*surgery
MH  - Heart Conduction System/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
EDAT- 2012/08/14 06:00
MHDA- 2012/12/18 06:00
CRDT- 2012/08/14 06:00
PHST- 2012/08/14 06:00 [entrez]
PHST- 2012/08/14 06:00 [pubmed]
PHST- 2012/12/18 06:00 [medline]
AID - 10.1111/j.1540-8167.2012.02348.x [doi]
PST - ppublish
SO  - J Cardiovasc Electrophysiol. 2012 Sep;23(9):988-95. doi: 
      10.1111/j.1540-8167.2012.02348.x. Epub 2012 Aug 7.