PMID- 22885886
OWN - NLM
STAT- MEDLINE
DCOM- 20130109
LR  - 20120831
IS  - 1473-6322 (Electronic)
IS  - 1473-6322 (Linking)
VI  - 12
IP  - 5
DP  - 2012 Oct
TI  - Molecular immunology of allergic conjunctivitis.
PG  - 534-9
LID - 10.1097/ACI.0b013e328357a21b [doi]
AB  - PURPOSE OF REVIEW: Successful treatment of allergic eye disease depends on 
      understanding the pathophysiology of ocular allergy. Thus, in this review, recent 
      experimental and clinical research that has provided significant information 
      about the immunopathology of allergic eye disease will be discussed. RECENT 
      FINDINGS: Recently, role of various cells, cytokines and chemokines has been 
      scrutinized in the immunopathogenesis of ocular allergy. In this respect, current 
      research highlights contribution of special molecules and cells in the 
      development and clinical features of immunoglobulin E (IgE) and T-cell-mediated 
      eye allergies. SUMMARY: Recent findings in molecular immunology of ocular 
      allergy, which comprise complex inflammatory conditions of the conjunctiva, have 
      enabled us to better understand the pathophysiology of these diseases and have 
      aided in the potential development of new therapeutic agents.
FAU - Irkec, Murat T
AU  - Irkec MT
AD  - Hacettepe University, Faculty of Medicine, Department of Ophthalmology, Ankara, 
      Turkey. mirkec@hacettepe.edu.tr
FAU - Bozkurt, Banu
AU  - Bozkurt B
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Allergy Clin Immunol
JT  - Current opinion in allergy and clinical immunology
JID - 100936359
RN  - 0 (Cytokines)
SB  - IM
MH  - Conjunctivitis, Allergic/*immunology/physiopathology
MH  - Cytokines/immunology/*metabolism
MH  - Eosinophils/immunology
MH  - Humans
MH  - Inflammation/immunology/physiopathology
MH  - Mast Cells/immunology
MH  - T-Lymphocytes/immunology
EDAT- 2012/08/14 06:00
MHDA- 2013/01/10 06:00
CRDT- 2012/08/14 06:00
PHST- 2012/08/14 06:00 [entrez]
PHST- 2012/08/14 06:00 [pubmed]
PHST- 2013/01/10 06:00 [medline]
AID - 10.1097/ACI.0b013e328357a21b [doi]
PST - ppublish
SO  - Curr Opin Allergy Clin Immunol. 2012 Oct;12(5):534-9. doi: 
      10.1097/ACI.0b013e328357a21b.