PMID- 2289498
OWN - NLM
STAT- MEDLINE
DCOM- 19910401
LR  - 20190828
IS  - 0301-5548 (Print)
IS  - 0301-5548 (Linking)
VI  - 61
IP  - 1-2
DP  - 1990
TI  - Glycogen and triglyceride utilization in relation to muscle metabolic 
      characteristics in men performing heavy-resistance exercise.
PG  - 5-10
AB  - Nine bodybuilders performed heavy-resistance exercise activating the quadriceps 
      femoris muscle. Intermittent 30-s exhaustive exercise bouts comprising 6-12 
      repetitions were interspersed with 60-s periods for 30 min. Venous blood samples 
      were taken repeatedly during and after exercise for analyses of plasma free fatty 
      acid (FFA) and glycerol concentration. Muscle biopsies were obtained from the 
      vastus lateralis muscle before and after exercise and assayed for glycogen, 
      glycerol-3-phosphate, lactate and triglyceride (TG) content. The activities of 
      citrate synthase (CS), lactate dehydrogenase, hexokinase (HK), myokinase, 
      creatine kinase and 3-hydroxyacyl-CoA dehydrogenase (HAD), were analysed. 
      Histochemical staining procedures were used to assess fibre type composition, 
      fibre area and capillary density. TG content before and after exercise averaged 
      (SD) 23.9 (13.3) and 16.7 (6.4) mmol kg-1 dry wt. The basal triglyceride content 
      varied sixfold among individuals and the higher the levels the greater was the 
      change during exercise. The glycogen content decreased (P less than 0.001) from 
      690 (82) to 495 (95) mmol kg-1 dry wt. and lactate and glycerol-3-phosphate 
      increased (P less than 0.001) to 79.5 (5.5) and 14.5 (7.3) mmol kg-1 dry wt., 
      respectively, after exercise. The HK and HAD/CS content respectively correlated 
      with glycogen or TG content at rest and with changes in these metabolites during 
      exercise. FFA and glycerol concentrations increased slightly (P less than 0.001) 
      during exercise. Lipolysis may, therefore, provide energy during heavy-resistance 
      exercise of relatively short duration. Also, storage and utilization of 
      intramuscular substrates appear to be influenced by the metabolic profile of 
      muscle.
FAU - Essen-Gustavsson, B
AU  - Essen-Gustavsson B
AD  - Swedish University of Agricultural Sciences, Faculty of Veterinary Medicine, 
      Department of Medicine and Surgery, Uppsala.
FAU - Tesch, P A
AU  - Tesch PA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Eur J Appl Physiol Occup Physiol
JT  - European journal of applied physiology and occupational physiology
JID - 0410266
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Triglycerides)
RN  - 9005-79-2 (Glycogen)
RN  - EC 1.1.1.- (3-Hydroxyacyl CoA Dehydrogenases)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.3.3.1 (Citrate (si)-Synthase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.3.2 (Creatine Kinase)
RN  - EC 2.7.4.3 (Adenylate Kinase)
SB  - IM
MH  - 3-Hydroxyacyl CoA Dehydrogenases/metabolism
MH  - Adenylate Kinase/metabolism
MH  - Adult
MH  - Citrate (si)-Synthase/metabolism
MH  - Creatine Kinase/metabolism
MH  - Exercise/*physiology
MH  - Fatty Acids, Nonesterified/blood
MH  - Glycogen/blood/*metabolism
MH  - Hexokinase/metabolism
MH  - Humans
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Lipolysis/physiology
MH  - Muscles/enzymology/*metabolism
MH  - Triglycerides/*metabolism
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
AID - 10.1007/BF00236686 [doi]
PST - ppublish
SO  - Eur J Appl Physiol Occup Physiol. 1990;61(1-2):5-10. doi: 10.1007/BF00236686.