PMID- 22898849 OWN - NLM STAT- MEDLINE DCOM- 20130926 LR - 20171116 IS - 1671-167X (Print) IS - 1671-167X (Linking) VI - 44 IP - 4 DP - 2012 Aug 18 TI - [Retrospective study of dysfunction transplant nephrectomy from a single-center within 10 years]. PG - 571-4 AB - OBJECTIVE: To find the reasons for dysfunction in renal graft. METHODS: A total of 27 patients with failed allografted kidneys underwent transplant nephrectomy from 2001 to 2010. The patients' data were collected separately. The pathologic diagnosis was made according to the Banff 2009 standard. RESULTS: All the operations were successful. The pathologic reports showed that 15 cases were acute rejection complicated with other factors (1 case was infected by Bacillus tuberculosis, 2 by mold, and 1 with IgA, 6 were found thrombus in operation), 6 cases were chronic rejection complicated with other factors [2 cases were acute rejection, and 2 cases were posttransplantation lymphoproliferative disorders (PTLD)], 4 cases were end-stage renal graft, and 2 PTLD alone. A total of 13 cases were human leukocyte antigen (HLA) mismatch, of which, 11 were confirmed as rejection. CONCLUSION: Rejection complicated with other factors is the most important reason for dysfunction in renal graft, such as thrombus and infection. HLA mismatch may cause the rejection. End-stage renal graft or PTLD also has an important position in the reason for nephrograft dysfunction. FAU - Qiu, Min AU - Qiu M AD - Department of Urology, Peking University Third Hospital, Beijing, China. FAU - Lu, Min AU - Lu M FAU - Ma, Lu-lin AU - Ma LL FAU - Hou, Xiao-fei AU - Hou XF FAU - Wang, Guo-liang AU - Wang GL FAU - Zhao, Lei AU - Zhao L LA - chi PT - English Abstract PT - Journal Article PL - China TA - Beijing Da Xue Xue Bao Yi Xue Ban JT - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences JID - 101125284 SB - IM MH - Adolescent MH - Adult MH - China/epidemiology MH - Delayed Graft Function/*etiology/physiopathology MH - Female MH - Graft Rejection/pathology/*physiopathology MH - Humans MH - Kidney Transplantation/*adverse effects MH - Lymphoproliferative Disorders/epidemiology MH - Male MH - Middle Aged MH - *Nephrectomy MH - Primary Graft Dysfunction/etiology/physiopathology MH - Retrospective Studies MH - Young Adult EDAT- 2012/08/18 06:00 MHDA- 2013/09/27 06:00 CRDT- 2012/08/18 06:00 PHST- 2012/08/18 06:00 [entrez] PHST- 2012/08/18 06:00 [pubmed] PHST- 2013/09/27 06:00 [medline] PST - ppublish SO - Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Aug 18;44(4):571-4.